DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hira and RACK1B_AT

DIOPT Version :9

Sequence 1:	NP_572401.2	Gene:	Hira / 31680	FlyBaseID:	FBgn0022786	Length:	1047	Species:	Drosophila melanogaster
Sequence 2:	NP_175296.1	Gene:	RACK1B_AT / 841284	AraportID:	AT1G48630	Length:	326	Species:	Arabidopsis thaliana

Alignment Length:	241	Identity:	64/241 - (26%)
Similarity:	100/241 - (41%)	Gaps:	47/241 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 HKD-CTKFATGGQGSDC-------GRVVIWNLLPVLSDKAEFDADVPKMLCQMDQHLACVNCVRW 78
            |.| .|..||....||.       ..:::|.|  ...||:...|.     .:|..|...|..|..
plant    14 HTDMVTAIATPVDNSDVIVTSSRDKSIILWKL--TKEDKSYGVAQ-----RRMTGHSHFVQDVVL 71

  Fly    79 SQNGQNLASGSDDKLIMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVY 143
            |.:||...|||.|..:.:|..:.|              ||.:.|.   ||..|||.:|:|.::..
plant    72 SSDGQFALSGSWDGELRLWDLATG--------------ESTRRFV---GHTKDVLSVAFSTDNRQ 119

  Fly   144 LASCSIDNTVIIWDAQA-FPHSVATLKGHTGLVKGVSWDP--LGRFLASQSDDRSIKIWNTMNWS 205
            :.|.|.|.|:.:|:... ..::::...||...|..|.:.|  |...:.|.|.|:::|:||..|..
plant   120 IVSASRDRTIKLWNTLGECKYTISEADGHKEWVSCVRFSPNTLVPTIVSASWDKTVKVWNLQNCK 184

  Fly   206 LSHTITEPFEECGGTTHILRLSWSPDGQYLVSAHAMNGGGPTAQII 251
            |.:|:      .|.:.::..::.||||....|      ||....|:
plant   185 LRNTL------AGHSGYLNTVAVSPDGSLCAS------GGKDGVIL 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hira	NP_572401.2	WD40	<12..370	CDD:225201	64/241 (27%)
		WD40	14..349	CDD:238121	64/241 (27%)
		WD40 repeat	16..68	CDD:293791	13/53 (25%)
		WD40 repeat	74..127	CDD:293791	13/52 (25%)
		WD40 repeat	132..169	CDD:293791	9/37 (24%)
		WD40 repeat	176..211	CDD:293791	12/36 (33%)
		WD40 repeat	223..263	CDD:293791	8/29 (28%)
		WD40 repeat	275..322	CDD:293791
		WD40 repeat	328..350	CDD:293791
		HIRA_B	423..442	CDD:286531
		Hira	629..820	CDD:284895
RACK1B_AT	NP_175296.1	WD40	6..321	CDD:238121	64/241 (27%)
		WD40 repeat	18..61	CDD:293791	11/49 (22%)
		WD40 repeat	67..103	CDD:293791	13/52 (25%)
		WD40 repeat	108..144	CDD:293791	9/35 (26%)
		WD40 repeat	153..190	CDD:293791	12/42 (29%)
		WD40 repeat	196..232	CDD:293791	8/29 (28%)
		WD40 repeat	237..279	CDD:293791
		WD40 repeat	297..321	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910