DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Hira and SPAC227.12

DIOPT Version :9

Sequence 1:NP_572401.2 Gene:Hira / 31680 FlyBaseID:FBgn0022786 Length:1047 Species:Drosophila melanogaster
Sequence 2:NP_592966.1 Gene:SPAC227.12 / 2541477 PomBaseID:SPAC227.12 Length:462 Species:Schizosaccharomyces pombe


Alignment Length:261 Identity:69/261 - (26%)
Similarity:103/261 - (39%) Gaps:72/261 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 DKQIFSVDIHKDCTKFATGGQGSDCGRVVIWN--------LLPVLSDKAE----------FDADV 59
            ::.|..|....:...||:|..|   |:|.:||        |....:|:..          :|||.
pombe   172 ERPIAIVRFSNNGNHFASGSWG---GQVKVWNSDNLSEVQLFRGHTDRVSGLDWYPLCQAWDADS 233

  Fly    60 PKM---------------------LCQMDQHLACVNCVRWSQNGQNLASGSDDKLIMIWRKSAG- 102
            .::                     |.:::.|||.|..|.:..:|..|.|.|.|....:|....| 
pombe   234 EQLTLATGAADNTVCLWKASQSTPLLRLEGHLARVGRVAFHPSGDYLVSASFDTTWRLWDVHTGV 298

  Fly   103 --------SSGVF-----------GTGGMQKNHESW-----KCFYTLRGHDGDVLDLAWSPNDVY 143
                    |.|:|           .:||.......|     |....|..|...::.:|||||...
pombe   299 ELLMQEGHSEGIFSIACQPDGSLVSSGGNDAIGRIWDLRSGKSIMVLDEHIRQIVAMAWSPNGYQ 363

  Fly   144 LASCSIDNTVIIWDAQAFPHSVA-TLKGHTGLVKGVSWDPLG--RFLASQSDDRSIKIWNTMNWS 205
            ||:.|.|:||.|||.:..  |:| |:..|:.||..|.:...|  ||:|:...|..:|:||.:|.|
pombe   364 LATSSADDTVKIWDLRKV--SLAHTIPAHSSLVSDVRYIESGVNRFIATSGYDGCVKLWNPLNCS 426

  Fly   206 L 206
            |
pombe   427 L 427

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HiraNP_572401.2 WD40 <12..370 CDD:225201 69/261 (26%)
WD40 14..349 CDD:238121 69/260 (27%)
WD40 repeat 16..68 CDD:293791 16/90 (18%)
WD40 repeat 74..127 CDD:293791 16/77 (21%)
WD40 repeat 132..169 CDD:293791 17/37 (46%)
WD40 repeat 176..211 CDD:293791 12/33 (36%)
WD40 repeat 223..263 CDD:293791
WD40 repeat 275..322 CDD:293791
WD40 repeat 328..350 CDD:293791
HIRA_B 423..442 CDD:286531
Hira 629..820 CDD:284895
SPAC227.12NP_592966.1 SFM 48..92 CDD:128776
WD40 174..460 CDD:238121 69/259 (27%)
WD40 <178..460 CDD:225201 68/255 (27%)
WD40 repeat 178..212 CDD:293791 10/36 (28%)
WD40 repeat 218..263 CDD:293791 4/44 (9%)
WD40 repeat 268..304 CDD:293791 9/35 (26%)
WD40 repeat 311..346 CDD:293791 5/34 (15%)
WD40 repeat 352..384 CDD:293791 15/33 (45%)
WD40 repeat 394..432 CDD:293791 13/34 (38%)
WD40 repeat 438..460 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.