| Sequence 1: | NP_572401.2 | Gene: | Hira / 31680 | FlyBaseID: | FBgn0022786 | Length: | 1047 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_005877.2 | Gene: | KATNB1 / 10300 | HGNCID: | 6217 | Length: | 655 | Species: | Homo sapiens |
| Alignment Length: | 626 | Identity: | 134/626 - (21%) |
|---|---|---|---|
| Similarity: | 221/626 - (35%) | Gaps: | 153/626 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 81 NGQNLASGSDDKLIMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVYLA 145
Fly 146 SCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMNWSLSHTI 210
Fly 211 TEPFEECGGTTHILRLSWSPDGQYLVSAHAMNGGGPTAQIIEREGWKCDKDFVGHRKAVTCVRFH 275
Fly 276 NSILSRQENDGSPSKPLQYCCLAVGSRDRSLSVW-------MTALQ-RPMVVIHELFNA------ 326
Fly 327 -----SILDLTWGPQECLLMACSVDGSIACLKFTEEEL-GKAISEEEQNAIIRKMYGKNYVNGLG 385
Fly 386 KSA--PVLEHPQRLLLPQGDKPTKFPLSNNNEANQRPISKQTETRTK--------DGKRRITPMF 440
Fly 441 IPLHEDGPTSLSMNIVSSSGSSTTALTSCSAAIGTLPAAAPTESAATPLMPLEPLVSKIDLGRLD 505
Fly 506 SRLKTQPASQRRQSLPFDPGQSNELL-RTPRLEEHQSSTCSPSNLNVT-----ATGKSEFVKAAL 564
Fly 565 ----------DYRLHVSNGH------LKTQHGMLAKV----------TASDSKEMLWEFYVGSPL 603
Fly 604 VNLNLCEKYAMLCSLDGSMRLIS-------------METGC 631 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Hira | NP_572401.2 | WD40 | <12..370 | CDD:225201 | 75/308 (24%) |
| WD40 | 14..349 | CDD:238121 | 69/286 (24%) | ||
| WD40 repeat | 16..68 | CDD:293791 | |||
| WD40 repeat | 74..127 | CDD:293791 | 10/45 (22%) | ||
| WD40 repeat | 132..169 | CDD:293791 | 6/36 (17%) | ||
| WD40 repeat | 176..211 | CDD:293791 | 10/34 (29%) | ||
| WD40 repeat | 223..263 | CDD:293791 | 10/39 (26%) | ||
| WD40 repeat | 275..322 | CDD:293791 | 12/54 (22%) | ||
| WD40 repeat | 328..350 | CDD:293791 | 4/21 (19%) | ||
| HIRA_B | 423..442 | CDD:286531 | 4/26 (15%) | ||
| Hira | 629..820 | CDD:284895 | 3/3 (100%) | ||
| KATNB1 | NP_005877.2 | Interaction with centrosomes | 1..300 | 75/311 (24%) | |
| Interaction with dynein. /evidence=ECO:0000250 | 1..284 | 71/295 (24%) | |||
| WD40 | 7..257 | CDD:238121 | 65/268 (24%) | ||
| WD40 repeat | 67..103 | CDD:293791 | 6/36 (17%) | ||
| WD40 repeat | 108..144 | CDD:293791 | 11/41 (27%) | ||
| WD40 repeat | 151..186 | CDD:293791 | 10/38 (26%) | ||
| WD40 repeat | 192..228 | CDD:293791 | 13/51 (25%) | ||
| WD40 repeat | 234..261 | CDD:293791 | 6/26 (23%) | ||
| Interaction with PAFAH1B1. /evidence=ECO:0000250 | 285..434 | 33/180 (18%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 311..422 | 24/134 (18%) | |||
| DNA_pol3_gamma3 | <386..>494 | CDD:331207 | 21/121 (17%) | ||
| Interaction with KATNA1 and NDEL1. /evidence=ECO:0000250 | 433..655 | 30/149 (20%) | |||
| Katanin_con80 | 497..648 | CDD:316447 | 18/85 (21%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||