Protein Alignment CHES-1-like and FHL1

DIOPT Version :10

• Sequence 1: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_015429.1
• Gene: FHL1 / 856219
• SGDID: S000006308
• Length: 936
• Species: Saccharomyces cerevisiae
• Alignment Length: 1080
• Identity: 201/1080 - (18%)
• Similarity: 318/1080 - (29%)
• Gaps: 420/1080 - (38%)

  Fly   260 HKGASGTTTVVEYKASKANQQQQNSPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTYLPTP 324
            |.|.|..||..::....:..:.|.:.:........:...:.:..:......:::..|.||
Yeast    13 HVGTSSPTTETQFTIDSSALKDQETKESITNSPTSEVPIETKLPKSSDIVTEEKHPQNTT----- 72

  Fly   325 TRTTMVGHGYMPVVVSSASQPILSPAKQQLPQQIYVTSNGSSPAGGGTIYKAASQALSSPTTSSS 389
              |.:......||...:.:      .|.:||..:   .|..           .|:.|.....:..
Yeast    73 --TDIENEVENPVTDDNGN------LKLELPDNL---DNAD-----------FSKLLEFDAKNDE 115

  Fly   390 SSSNTTTHHPHKKYLREKMHVQMDHSSHVASTVTVVSSPASSNNSSISSSNTGSVSGSGSSTAAV 454
            :..|:.....|.......:.:..|||..|:|...:...|.:.:......:.        .:||||
Yeast   116 ALFNSNELLSHTMDPVNNIDLTHDHSREVSSKEDINIEPVNPDEDEREKTQ--------DNTAAV 172

  Fly   455 NGGNSPVPKTSSFSTVFEAVNYATSAASNSSSSSNSTPNSQAILHGQESPAVVTTTTLISAGTLP 519
                    ||.....            |..:|.....|.:.||.......:|...|.     |||
Yeast   173 --------KTEGIRN------------SEDTSIQKDEPTADAIYTDVHKLSVNKDTE-----TLP 212

  Fly   520 PGYSFVNQVASTPHVLS---TPAHVASPE---TPPGAALLPGTYYATSTTSAGTTTTTLQARSLQ 578
               :.|::..:..|:.:   ||......|   .||     ..|....::|.|.||...|   |..
Yeast   213 ---TLVDEKNNMLHMRNNSITPIMFQQHELVGQPP-----QNTVTENNSTDAETTQRKL---SEP 266

  Fly   579 LSVSPPPPNMTPT---------------SQVHNGSLGGGGGGGGGSGGGGGGGGANLRSPNSYAS 628
            :..|.|.||..||               .|..:..:|                   .||.|.: |
Yeast   267 IDASLPLPNEQPTIFAYARLDFQSFTFYVQTLHAIIG-------------------RRSENDF-S 311

  Fly   629 YDNEDSLKEFDLVVSSRLHT------STPQYSVSKNGANG---------YGN------------- 665
            :..:.:|.....:  ||.|.      .|.::.:|..|.||         .||
Yeast   312 HKVDVNLGPSKSI--SRRHAQIFYNFGTGRFELSIIGKNGAFVDDIFVEKGNTVPLRNKTKIQIG 374

  Fly   666 -------------------------GNSNVNGSGAGSNTPQKQK------HPNNVPYDPLVHTNN 699
                                     ..|.:|......|.|:.:|      .|......|.|....
Yeast   375 QIPFQFILPEQERNDDSKSPENADIAESEINTRNLKKNEPKSKKKITTGAKPKKAQTKPAVKKEK 439

  Fly   700 KPP---------------------YSFSSLIFMAI-EGSNEKALPVKEIYAWIVQHFPYFKTAPN 742
            |||                     .|:|:::...| :.|..|.:.:.||||.|.:.|||:|..|:
Yeast   440 KPPKIPKKVYTLEEIPVEYRTKPTVSYSAMLTTCIRKYSTAKGMSLSEIYAGIRELFPYYKYCPD 504

  Fly   743 GWKNSVRHNLSLNKSFVKVEKAPNMGKGSLW------------------------------RVEP 777
            ||::||||||||||||.||.|.   |||.||                              ::|.
Yeast   505 GWQSSVRHNLSLNKSFRKVSKE---GKGWLWGLDEEYIAERERQKKKQSEIAVAKAQAAQLKLEQ 566

  Fly   778 QQ------------------------RQNLIQAL-------NRSPFFPNSAVDK----------- 800
            ||                        :||:.|.|       ||.    |:|.|.
Yeast   567 QQHKLQQVPQRGKKDIVSQRSNVNARKQNISQTLAANRAASNRK----NTASDNQRTMKYLQEQL 627

  Fly   801 ----------------------ISPSLKSPSGGSAYDSLDGGGSGSVSSAQPVAGGAGVPAAAAV 843
                                  ::.::...:..:....:.|....::....|......:.||...
Yeast   628 VILTRDRKGLSKQVIAAILTQALAMTINQVTQAAKNKGITGNPLTALMDKNPQHLNLILAAAVNA 692

  Fly   844 ALSTPTKSNGLALANGASQATNA----------------ARPHSPN------GGGSGSH------ 880
            |.:..||.....|.|..:.|..|                ..||.|:      ...:.||
Yeast   693 ATAKVTKGEVKQLVNPETTAAAALAAKAQHSKPIRQPIVQTPHVPDRPPSQLSASASSHPNNYLH 757

  Fly   881 ----ARFDPYLFPNLSKAF---RNIR---------------EDTVGQPMLQDALDDELSGDYHNN 923
                ..|||   .:||:.|   :|.|               ::...||..:.|.|::|..:...:
Yeast   758 DKQPGSFDP---SSLSRFFQPRQNARATSSVAATSVPAAASQNVDAQPKPKPAQDNDLESESGTS 819

  Fly   924 NNNNSGSKYNYMGANGSGGAGSGGVGSNANGASDGINFARLARDCGADSIDDVHAAAAMLYLKHG 988
            ::::|.|:......:||....:.|.|.|::
Yeast   820 SSSSSSSESGSESDSGSDDGSASGSGDNSS----------------------------------- 849

  Fly   989 PKIYSEPFQNGSGPVITSSPSEDHTYSAGGNSNADSGSSTPLTNGNALASVAQAVAQGQNNQGGA 1053
                            |||.||         |.:||||.....|.......::::   :||:
Yeast   850 ----------------TSSESE---------SESDSGSEVDEKNNKNEKIDSESI---KNNE--- 883

  Fly  1054 GSDSNCASSDAAYDSSEENHNI--TPEEMADRQRHRDGVD 1091
             |..:..|.|.  :||.:|..|  |.||..|.:|.:...|
Yeast   884 -SKDDIPSKDE--NSSNDNREISKTDEEGHDSKRRKVSED 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	40/126 (32%)
FHL1	NP_015429.1	COG5025	18..739	CDD:227358	150/820 (18%)