Protein Alignment CHES-1-like and FKH2

DIOPT Version :10

• Sequence 1: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_014331.3
• Gene: FKH2 / 855656
• SGDID: S000005012
• Length: 862
• Species: Saccharomyces cerevisiae
• Alignment Length: 977
• Identity: 191/977 - (19%)
• Similarity: 327/977 - (33%)
• Gaps: 295/977 - (30%)

  Fly   388 SSSSSN-------TTTHHPHKKYLREKMHVQMDHSSHVASTVTVVSSPASSNNSSISSSNTGSVS 445
            |||:.|       |.|::...||..:      .|...:.:.::.:::|......|:..||..:::
Yeast     2 SSSNFNEMNELNMTQTNYGSTKYTAQ------HHQGVINAIISSLTAPDQPTTVSLQYSNDKNMA 60

  Fly   446 GSGSSTAAVNG--------------GNSPVPKTSSFSTVFEA------VNYATSAASNSS----- 485
            ....:.|.::|              |.:..|..|:.....:.      ||.....|...|
Yeast    61 TEIQAYAKLSGPNWTYYVKDLEVSIGRNTDPLNSALQENSDGVKNSYRVNIDLGPAKVVSRKHAI 125

  Fly   486 ---------------SSSNSTPNSQAILHGQESPAV-VTTTTLISAGTLPPGYSFVNQVASTPHV 534
                           ..:.:..|.|...:|..:|.: :::.||:..|
Yeast   126 IKYNMNIGGWELHILGRNGAKVNFQRTHNGPNNPPIRLSSGTLLDIG------------------ 172

  Fly   535 LSTPAHVASPETPPGAA------LLPGTYYATSTTSAGTTTTTLQ--------ARSLQLSVSPPP 585
             .|......|::.|..|      |:|........  .|.....|:        |:..||
Yeast   173 -GTQMMFILPDSDPVVAPICIEHLMPNLINMFGL--EGNNNPLLRDIIKQSNYAKQRQL------ 228

  Fly   586 PNMTPTSQVHNGSLGGGGGGGGGSGGGGGGGGANLRSPNSYASYDNEDSLKE----FDLVVSSRL 646
               |...|:....|.|.|      |....|.|||| .|:....::|.::.|.    |..:..:..
Yeast   229 ---TSNQQIKGFKLYGSG------GNAPFGSGANL-GPSEQGIFNNNNNSKNKNGYFTSINPNYT 283

  Fly   647 HTSTPQYSVSKNGANGYGNGN----SNVNGSGAGSNT-PQKQKHPNNVPYDPLVHTNNKPPYSFS 706
            .::|...:::...|:..|..|    :|...|...||. ||.....:::.:|.  :.|.|||:|::
Yeast   284 ASTTTSNTINPQAASPQGPPNTIIAANFVDSYKSSNAYPQALDFTSDLSHDE--NRNVKPPHSYA 346

  Fly   707 SLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVKVEKAPN-MGKG 770
            ::|..||..|.|..:.:.:||.:|..::.|::.|.:||:||:||||||||:|.||.:.|| .|||
Yeast   347 TMITQAILSSPEGVISLADIYKYISSNYAYYRFAKSGWQNSIRHNLSLNKAFEKVPRRPNEPGKG 411

  Fly   771 SLWRVEPQQRQNLIQALNRSPF----------------------FPNSAVDKISPSLKSPSGG-- 811
            ..||:....:|..:...|....                      .|.....::|.::..|...
Yeast   412 MKWRISESYQQEFLNKWNTGKVGKIRRGSSVARQLQLHMAKFNSLPMEMDYRLSLNMAQPPKRQL 476

  Fly   812 SAYDSLDGGGSGSVSS-AQPVAGGAGVPAAAA--------------------------------- 842
            .:::.|:...:..:.. .|.|.....:||:..
Yeast   477 QSHNVLEPSNNNIIEGFVQHVPSKGNLPASQQSQPPVSHQNQSQQPPPQEQRQEIQFTFADTQNR 541

  Fly   843 -VALSTPTK--------SNGLALANGASQATNAARP----------HSPNGGGSGSHARFDPYLF 888
             :||:.|.|        ||.....|...:...:..|          .|||..         ...|
Yeast   542 NIALARPIKTPQLQAPNSNANLNQNNMKEYKESLHPPAISISQMNRQSPNNA---------LVSF 597

  Fly   889 PNL---SKAFRNIREDTVGQPMLQDALDDELSGDYHNNNNNNSGSKYNYMGANGSGGAGSGGV-- 948
            .|.   ||...||          .|:.|        .:.|||.|:|.|....:.|....:|.:
Yeast   598 TNACANSKIINNI----------SDSAD--------KSTNNNGGTKMNLPAISTSSLDENGNLEP 644

  Fly   949 -----GSNANGA-SDGINFARLARDCGADSIDDVHAAAAMLYLKHGPKIYSEPFQNGSGPVITSS 1007
                 ..|:|.. ..|...:.||    |:|:.                 .|:|:.     .:..|
Yeast   645 TTTTSSGNSNSVPQTGTTTSSLA----ANSLR-----------------LSQPYD-----TLLRS 683

  Fly  1008 PS--------EDHTYSAGGNSNADS--GSSTPLTNGNALASVAQAVAQGQNNQGGAGSDSNCASS 1062
            |:        |.:|...|..:.|.|  .|::..||.|...:.....:..:|.|.|...|||...|
Yeast   684 PTKAFHITAMEAYTPERGSANRARSPLHSNSNNTNNNGANNSNLQTSGMENKQTGLVLDSNVLKS 748

  Fly  1063 DAAYDSSEENHNITPE-EMADRQRHRDGVDALLSLSGSSIVECGSVATTHYHSNGSSGSSHG--- 1123
               .:|:.:|..:||. ..:...:...||..||..|          :|.:..:..|.|:..|
Yeast   749 ---MESNNDNRRLTPSTSKSQNVKSSPGVWNLLQFS----------STNNTPAADSGGNKRGFSI 800

  Fly  1124 SPHKRASSHSLEEEHLQQHREQQLQQQQQQQQHHHQQFGSSQAVYTNGS--GSKMALLSSAAANV 1186
            :|..:|.    |.|:....::........:.    :...||......||  .:|..:|.:..|.:
Yeast   801 NPDIKAK----ENENATSEKDSDSNSNDLET----KDINSSPLKNQGGSTANAKELILDTDGAKI 857

  Fly  1187 AL 1188
            ::
Yeast   858 SI 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	35/75 (47%)
FKH2	NP_014331.3	COG5025	1..610	CDD:227358	128/661 (19%)