DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CHES-1-like and foxc1b

DIOPT Version :9

Sequence 1:NP_001259311.1 Gene:CHES-1-like / 31678 FlyBaseID:FBgn0029504 Length:1268 Species:Drosophila melanogaster
Sequence 2:NP_571804.1 Gene:foxc1b / 79375 ZFINID:ZDB-GENE-010302-2 Length:433 Species:Danio rerio


Alignment Length:489 Identity:117/489 - (23%)
Similarity:164/489 - (33%) Gaps:201/489 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly   614 GGGGANLRSPNSYASYDNEDSLKEFDLVVSSRLHTSTPQYSVSKNGANGYGNGNSNVNGSGAGSN 678
            |||...:.:|.|..|                  |.:..||....  |..||              
Zfish    31 GGGYTGMPAPMSMYS------------------HATHEQYPGGM--ARAYG-------------- 61

  Fly   679 TPQKQKHPNNVPYDPLVHTNN--KPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAP 741
                       ||.|.....:  |||||:.:||.|||:.|::|.:.:..||.:|::.||:::...
Zfish    62 -----------PYAPAQQPKDMVKPPYSYIALITMAIQNSSDKKITLNGIYQFIMERFPFYRDNK 115

  Fly   742 NGWKNSVRHNLSLNKSFVKV---EKAPNMGKGSLWRVEP-------------------------- 777
            .||:||:|||||||:.||||   :|.|  ||||.|.::|                          
Zfish   116 QGWQNSIRHNLSLNECFVKVPRDDKKP--GKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVLRE 178

  Fly   778 ------QQRQNLIQALNR------------------SPFFPNSAVDKIS--PSLKSP--SGGSAY 814
                  |.:.|..||..:                  :|  |:.:...:|  |..:||  |||||.
Zfish   179 KEDRDRQGKDNPGQACEQDAQQPVKLRDIKTENGACTP--PHDSTPPLSTVPKTESPDRSGGSAC 241

  Fly   815 DSLDGGGSGSVSSAQPVAGGAGVPAAAAVALSTPTKSNGLALANGASQ------ATNAARP---- 869
                   |||..|..|           ..|.|..|...||   .|:.|      |:.||.|    
Zfish   242 -------SGSPQSQTP-----------QQAFSMDTIMTGL---RGSPQHAAELPASRAALPGSVS 285

  Fly   870 --HSPNGGGSGSHARFDPYLFPNLSKAFRNIREDTVGQP------MLQDAL--------DDELSG 918
              :||    :...|.:.|                ..|||      |...:|        ||.|. 
Zfish   286 LTYSP----TPQPAHYSP----------------PCGQPATYHCNMQATSLYTGDRGHGDDTLP- 329

  Fly   919 DYHNNNNNNSGSK---------------------YNYMGANGSGGAGSGGVGSNANGASDGINFA 962
            :|.|..|.:|.|.                     .|..|..|...|...|...|.:...:.....
Zfish   330 EYTNTTNASSISHPHQSSSQESQHLQQNRLAPWYLNQSGELGHLSASYPGQQQNFHAVREMFETQ 394

  Fly   963 RLARD----CGADSIDDVHAAAAMLYLKHGPKIY 992
            |:|.:    .|::|......::..||...|..:|
Zfish   395 RIALNSSPVTGSNSCQMAFPSSQPLYRASGAFVY 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CHES-1-likeNP_001259311.1 Forkhead 700..785 CDD:278670 42/119 (35%)
foxc1bNP_571804.1 Forkhead 74..160 CDD:278670 40/87 (46%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 174..250 19/84 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..355 8/37 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1270467at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.820

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