DRSC/TRiP Functional Genomics Resources

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Protein Alignment CHES-1-like and foxh1

DIOPT Version :10

Sequence 1:NP_511071.3 Gene:CHES-1-like / 31678 FlyBaseID:FBgn0029504 Length:1268 Species:Drosophila melanogaster
Sequence 2:NP_571577.1 Gene:foxh1 / 57930 ZFINID:ZDB-GENE-000616-15 Length:472 Species:Danio rerio


Alignment Length:478 Identity:113/478 - (23%)
Similarity:169/478 - (35%) Gaps:140/478 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   640 LVVSSRLHTSTPQYSVSKNGANGYGNGNSNV-NGSGAGSNTPQKQKHPNNVPYDPLVHTNNKPPY 703
            |.:..||..||.....|...|.....|...: :|:.:|......|::|             ||||
Zfish    49 LELGGRLDKSTGMAQDSCYRAKATNQGPWELQDGNSSGGKKKNYQRYP-------------KPPY 100

  Fly   704 SFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVKVEKAPN-- 766
            |:.::|.|.|:.|.||.|.:.||...|...||:||....||::|||||||....||||.|.|.  
Zfish   101 SYLAMIAMVIQNSPEKKLTLSEILKEISTLFPFFKGNYKGWRDSVRHNLSSYDCFVKVLKDPGKP 165

  Fly   767 MGKGSLWRVEPQ-------QRQN--------LIQALNRSPFF--------------PNSAVDKIS 802
            .|||:.|.||..       :|||        .|.|.:.:|:.              |.|::..: 
Zfish   166 QGKGNFWTVEVNRIPLELLKRQNTAVSRQDETIFAQDLAPYIFQGYSQPNKSKPLPPESSLPPV- 229

  Fly   803 PSLKSPSGGS-----------AYDSLDGGGSGSVSSAQPV-AGGAGVPAAAAVALSTPTKSNGLA 855
            |:.:||....           |.|||       :.|.:|. :.|.|:....:..:..|..     
Zfish   230 PTRQSPPPSEDPYRPKLDSTFAIDSL-------LHSLRPASSAGEGLRERESWGVGPPPH----- 282

  Fly   856 LANGASQATNAARPHSPNGGGSGSHARFDPYLFPNLSKAFRNIREDTVG----------QPMLQD 910
                 :::|...||.:.:..||.|.:...|      :..|.:  ||..|          :.:..|
Zfish   283 -----TRSTTPPRPCNASYNGSSSASSVSP------ASDFSD--EDWRGVTVVGKRSGDRGITSD 334

  Fly   911 ALDDELSGDYHNNNNNN--------SGSKYN--------YMGANGSGGAGSGGVGSNANGASDGI 959
            |..|.......::...|        |.:||.        .|..||:.....||:.....|.:   
Zfish   335 AYSDSCPPPNKSSKRGNTPPWELPTSYAKYTPPNAVAPPSMRFNGNPFMPLGGIPFYGYGGA--- 396

  Fly   960 NFARLARDCGADSIDDVHAAAAML-------YLKHGP-KIYSEPFQNGSGPVITSSPSEDHTYSA 1016
                             |...:.|       .|..|| .|.:.|.......::.|.|.....:.|
Zfish   397 -----------------HVTTSHLIGHPYWPILPSGPVSIQAPPLLMDLDSMLQSVPPNKSVFDA 444

  Fly  1017 GGNSNA---DSGSSTPLTNGNAL 1036
            .|::|.   .|.:...|.||.:|
Zfish   445 LGSNNQTVHPSPNQYALQNGPSL 467

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CHES-1-likeNP_511071.3 FH_FOXN2-like 700..775 CDD:410805 38/76 (50%)
foxh1NP_571577.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 36..56 2/6 (33%)
FH_FOXH 97..175 CDD:410796 38/77 (49%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 211..246 5/35 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 261..360 19/116 (16%)
SMAD-interaction domain (SID) 339..465 25/145 (17%)
Fast/FoxH1 motif 1 (FM1) 357..361 0/3 (0%)
Fast/FoxH1 motif 2 (FM2) 367..373 0/5 (0%)
SMAD interaction motif (SIM) 428..448 4/19 (21%)

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