Protein Alignment CHES-1-like and foxo4

DIOPT Version :10

• Sequence 1: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_009289443.1
• Gene: foxo4 / 563719
• ZFINID: ZDB-GENE-150311-1
• Length: 626
• Species: Danio rerio
• Alignment Length: 690
• Identity: 150/690 - (21%)
• Similarity: 226/690 - (32%)
• Gaps: 199/690 - (28%)

  Fly   580 SVSPPPPNMTPTSQVHN----------GSLGGGGGGGGGSGGGGGGGGANLRSPNSYASYDNEDS 634
            :|.|..|:..|.::..:          .::..||..|..|..|         :|.:     .||.
Zfish     5 NVPPIDPDFEPQTRPRSCTWPLPRPDISAVKAGGTDGSESAAG---------TPPA-----EEDK 55

  Fly   635 LKEFDLVVSSRLHTSTP------QYSVSKNGANGYGNGNSNVNGSGAGSNTPQKQKHPNNVPYDP 693
                        |...|      :.:||:.|.           .:|.|..||:|.....|.
Zfish    56 ------------HDPQPIICDPEKIAVSEGGL-----------VAGVGGATPRKGSSRRNA---- 93

  Fly   694 LVHTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFK-----TAPNGWKNSVRHNLS 753
               ..|:   |::.||..|||.|.||.|.:.:||.|:|:..||||     .:..|||||:|||||
Zfish    94 ---WGNQ---SYADLISQAIENSPEKRLTLAQIYDWMVKTVPYFKDKGDSNSSAGWKNSIRHNLS 152

  Fly   754 LNKSFVKVEKAPNMGKGSLWRVEPQQRQNLIQALNRSPFFPNSAVDKISPS------LKSPSGGS 812
            |:..|::|.. .:.||.|.|.:.|:..:.......|:....||.  |:..|      .|..:|.:
Zfish   153 LHNKFLRVHN-ESTGKSSWWMLNPEGGKTGKAHRRRATSMDNSG--KLLKSRIRAKQTKKQAGAA 214

  Fly   813 AYDSLDGGGSGSVSSAQPVAGGAGVPAAA---AVALSTPTKSNGLALANGASQATNAARPHSPNG 874
            ......||..|..:|....|...|.|...   .|..|:|:....|    .......:.||.:.:.
Zfish   215 GIGGTGGGLQGEGTSGTGNADSPGPPGQFGKWGVNSSSPSSRGSL----DDPDIWTSIRPRTSSN 275

  Fly   875 GGSGSHARFDPYLFPNLSKAFRNIREDTVGQPMLQDALDDELSGDYHNNNNNNSGSKYNYMGANG 939
            ..:.| .|..|.               ..||....|..:|.|.|.|
Zfish   276 ASTLS-GRLSPI---------------ATGQEDEDDLPEDGLLGGY------------------- 305

  Fly   940 SGGAGSGGVGSNAN-------GASDGINFARLARDCGADSI------DDVHAAAAMLYLKHGPKI 991
                .||.:.|...       ...||:......:...:.|:      ..:.:|:.:|     |:.
Zfish   306 ----SSGNLPSTLPETLMEELDLIDGLTLMTAPQGGASPSMAPPAPPQPLPSASTLL-----PRG 361

  Fly   992 YSEPFQNGSGPVITSSPSEDHTYSAGGNSNADSGSSTPLTNGNALASVAQAVAQGQNNQGGAGSD 1056
            .|.|......|...|..|......:....||.|.:|:|...||:|.|...       ..|.:|..
Zfish   362 SSFPSFRQLQPTKASQGSTPPGPQSSVQPNAGSSTSSPSNFGNSLFSPLP-------GPGHSGFS 419

  Fly  1057 SNCASSDAAYDSSEENHNITPEEM----ADRQRHRDGVDALLSLSG---SSIVECGSVATTHYHS 1114
            ::..||..|..:|:   :..|.::    .|......|...||.|.|   ||.|:.|.:..    |
Zfish   420 THVPSSLEALLTSD---SPPPSDVMMTQMDPLMPSQGGGGLLGLGGSMSSSQVKAGQMML----S 477

  Fly  1115 NGSSGSSHGSPHKRASSHSLEEEHLQQHREQQLQQQQQQQQHHHQQFGSSQAVYTNGSGSKMALL 1179
            .|...|:.|                      |:..|:..|..|.|.          |.|.....:
Zfish   478 KGIDTSTVG----------------------QMSLQRPPQLQHSQM----------GFGMMHMAM 510

  Fly  1180 SSAAANVALAQQQQQ-----QIHQDMYSSTAGHNASMYLG 1214
            |.....::..:.|.|     .:|..:..|.||:.....||
Zfish   511 SQEPPQLSTVKTQHQVPGSGLLHHGVIPSPAGNGGLQGLG 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	35/79 (44%)
foxo4	XP_009289443.1	FH_FOXO4	91..176	CDD:410836	37/95 (39%)
		FOXO_KIX_bdg	375..>450	CDD:465228	19/84 (23%)
		FOXO-TAD	564..603	CDD:435506