DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CHES-1-like and FOXJ2

DIOPT Version :9

Sequence 1:	NP_001259311.1	Gene:	CHES-1-like / 31678	FlyBaseID:	FBgn0029504	Length:	1268	Species:	Drosophila melanogaster
Sequence 2:	XP_011519062.1	Gene:	FOXJ2 / 55810	HGNCID:	24818	Length:	591	Species:	Homo sapiens

Alignment Length:	503	Identity:	132/503 - (26%)
Similarity:	193/503 - (38%)	Gaps:	146/503 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   630 DNEDSLKEFDLVVSSRLHTSTPQYSVSKNGANGYGNGNSNVNGSGAGSNTPQKQKHPNNVPYDP- 693
            |.|.||...|.     |...|.:.::.|.|           :.|.||.....::..|.: |.||
Human     4 DLESSLTSIDW-----LPQLTLRATIEKLG-----------SASQAGPPGSSRKCSPGS-PTDPN 51

  Fly   694 --------LVHTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRH 750
                    .||.:.||.||:::||..||..|..|.:.:.|||.||..:|||:|.|..|||||:||
Human    52 ATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRH 116

  Fly   751 NLSLNKSFVKVEK-APNMGKGSLWRVE--PQQRQNLIQALNRSPFFPNSAVDKISP---SLKSPS 809
            ||||||.|.||.: ..:.||||.|.::  |.     |....|.|  |:..:.:.||   :.|||.
Human   117 NLSLNKCFRKVPRPRDDPGKGSYWTIDTCPD-----ISRKRRHP--PDDDLSQDSPEQEASKSPR 174

  Fly   810 GGSAYDSLDGGGSGSVSSAQPVAGGAGVPAAAAVALSTPTKSNGL----ALANGASQATNAARP- 869
            ||.|       |||..|  .|..|...:...:..::::.::..|.    |:|.|||...:|..|
Human   175 GGVA-------GSGEAS--LPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPP 230

  Fly   870 --HSPNGGGSGSHARFDPYLFPNLSKAFRNIREDTVGQPMLQDALD------DELSGDYHNNNNN 926
              ::.|.....|::..:   |.:||.:|||:.:.     ||:.:..      ..|.||...:||
Human   231 PLYNTNHDFKFSYSEIN---FQDLSWSFRNLYKS-----MLEKSSSSSQHGFSSLLGDIPPSNN- 286

  Fly   927 NSGSKYNY-----------------------------MGANGSGGAGSGGVGSNANGASDGINFA 962
                .|.|                             ..|...|.:..||.......::||.. .
Human   287 ----YYMYQQQQPPPPQQQQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCT-P 346

  Fly   963 RLARDCGADSIDDVHAAAAMLYLKHGP----KIYSEPFQNGSGPVITSSPSEDHTYSAGGNSNAD 1023
            ...:..||:.              :||    .::..|.|:|.     ..|.:.|.:|       .
Human   347 PGGKQAGAEG--------------YGPPPVMAMHPPPLQHGG-----YHPHQHHPHS-------H 385

  Fly  1024 SGSSTPLTNGNALASVAQAVAQGQ---NNQGGAGSDSNCASSDAAYDS 1068
            .....|         ..|..||||   ||.|.|.....|::.|:..:|
Human   386 PAQQPP---------PPQPQAQGQAPINNTGFAFPSDWCSNIDSLKES 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_001259311.1	Forkhead	700..785	CDD:278670	42/87 (48%)
FOXJ2	XP_011519062.1	Forkhead	66..143	CDD:278670	41/76 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910