Protein Alignment CHES-1-like and FOXN2

DIOPT Version :9

• Sequence 1: NP_001259311.1
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_001362371.1
• Gene: FOXN2 / 3344
• HGNCID: 5281
• Length: 431
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 141/557 - (25%)
• Similarity: 203/557 - (36%)
• Gaps: 204/557 - (36%)

  Fly   630 DNEDSLKEFDLVVSSRLHTSTPQYSVSKNGANGYGNGNSNVNGSGAGSNTPQKQKHPNNVP-YDP 693
            |:|.:  :.:|...:.||.||...:            |.::...|....:|......::|| :.|
Human    48 DSESA--DDELTNLNWLHESTNLLT------------NFSLGSEGLPIVSPLYDIEGDDVPSFGP 98

  Fly   694 LVHTN-------NKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHN 751
            ..:.|       :|||||||.||:||||.|..|.|||||||:||:.|||||.|||.|||||||||
Human    99 ACYQNPEKKSATSKPPYSFSLLIYMAIEHSPNKCLPVKEIYSWILDHFPYFATAPTGWKNSVRHN 163

  Fly   752 LSLNKSFVKVEKAPNM--GKGSLWRVEPQQRQNLIQALNRSPFFPNSAVDKISPSLKSPSGGSAY 814
            |||||.|.|||::...  ||||||.|:|:.:.||||||.:.||               .|..|..
Human   164 LSLNKCFQKVERSHGKVNGKGSLWCVDPEYKPNLIQALKKQPF---------------SSASSQN 213

  Fly   815 DSLDGGGSGSVSSAQPVAG--GAGVPAAAAVALSTPTKSNGLALANGASQATNAARPHSPNGGGS 877
            .||......||.....|..  .:.:.||||:.|...:...|:....
Human   214 GSLSPHYLSSVIKQNQVRNLKESDIDAAAAMMLLNTSIEQGILECE------------------- 259

  Fly   878 GSHARFDPYLFPNLSKAFRNIREDTVGQPM-LQDALDDELSGDYHNNNNNNSGSKYNYMGANGSG 941
                                       :|: |:.||..:.|          .|:.:::..|
Human   260 ---------------------------KPLPLKTALQKKRS----------YGNAFHHPSA---- 283

  Fly   942 GAGSGGVGSNANGASDGINFARLAR-DCGADSIDDVHAAAAMLYLKHGPKIYSEPFQNGSGPVIT 1005
                                .||.. |..|.|||
Human   284 --------------------VRLQESDSLATSID------------------------------- 297

  Fly  1006 SSPSEDHTYSAGGNSNADSGSSTPLTNGNALASVAQAVAQGQNNQGGAGSDSNCASSDAAYDSSE 1070
              |.|||.|||...:.....|.:.:::.:::..|.:.:.:               :|....|.||
Human   298 --PKEDHNYSASSMAAQRCASRSSVSSLSSVDEVYEFIPK---------------NSHVGSDGSE 345

  Fly  1071 ENHNITPEEMADRQRHRDGVDALLSLSGSSIVECGSVATTHYHSNGSSGSSHGSPHKRASSHSLE 1135
            ..|:   ||..|    .|..|..|..||.:...|..::     ..|.||..    .::.:...::
Human   346 GFHS---EEDTD----VDYEDDPLGDSGYASQPCAKIS-----EKGQSGKK----MRKQTCQEID 394

  Fly  1136 EE---------HLQQHR--------EQQLQQQQQQQQ 1155
            ||         ||...|        ..:.|.|:|:::
Human   395 EELKEAAGSLLHLAGIRTCLGSLISTAKTQNQKQRKK 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_001259311.1	Forkhead	700..785	CDD:278670	60/86 (70%)
FOXN2	NP_001362371.1	FH_FOXN2	111..192	CDD:410832	57/80 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..387		6/31 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	126	1.000	Domainoid score	I5426
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005460
OrthoInspector	1	1.000	-	-		otm41006
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5832
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.890