Protein Alignment CHES-1-like and FOXA3

DIOPT Version :10

• Sequence 1: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_004488.2
• Gene: FOXA3 / 3171
• HGNCID: 5023
• Length: 350
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 119/459 - (25%)
• Similarity: 157/459 - (34%)
• Gaps: 176/459 - (38%)

  Fly   541 VASPETP-PGAALLPGTYYATSTTSAGTTTTTLQARSLQLSVSPPPPNMTPTSQVHNGSLG---- 600
            |.||.|| |..|.| .:|...:..|                 ||.||...|.|.:.:|.|.
Human    24 VYSPVTPVPTMAPL-NSYMTLNPLS-----------------SPYPPGGLPASPLPSGPLAPPAP 70

  Fly   601 ---------GGGGGGGGSGGGGGGGGANLRSPNSYASYDNEDSLKEFDLVVSSRLHTSTPQYSVS 656
                     |.|..||.|..|.|..|..|                         :|
Human    71 AAPLGPTFPGLGVSGGSSSSGYGAPGPGL-------------------------VH--------- 101

  Fly   657 KNGANGYGNGNSNVNGSGAGSNTPQKQKHPNNVPYDPLVHTNNKPPYSFSSLIFMAIEGSNEKAL 721
                               |...|:..:.       ||.|.  |||||:.|||.|||:.:..|.|
Human   102 -------------------GKEMPKGYRR-------PLAHA--KPPYSYISLITMAIQQAPGKML 138

  Fly   722 PVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVKVEKAPNM-GKGSLWRVEPQQRQNLIQ 785
            .:.|||.||:..|||::.....|:||:||:||.|..||||.::|:. ||||.|.:.|.. .|:.:
Human   139 TLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWALHPSS-GNMFE 202

  Fly   786 ---ALNRSPFFPNSAVDKISPSLKSPSGGSAYDSLDGGGSGSVSSAQPVAGGAGVPAAAAVALST 847
               .|.|...|      |:...:|.            ||||:.::.:   .|.|    :|.:.:|
Human   203 NGCYLRRQKRF------KLEEKVKK------------GGSGAATTTR---NGTG----SAASTTT 242

  Fly   848 PTKSNGLALANGASQATNAARPHSP------NGG------GSGSHARFDPYLFPNLSKAFRNIRE 900
            |           |:..|:..:|..|      .||      ..||.|...|| |..|.
Human   243 P-----------AATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPY-FTGLE-------- 287

  Fly   901 DTVGQPMLQDALDDELSGDYHNNNN-----NNSGSKYNYMGANGSGGAGSGGVGSNANGASDGIN 960
                       |..||..|...|.|     ||..|:..  .|......|.||.|  |.|...|:.
Human   288 -----------LPGELKLDAPYNFNHPFSINNLMSEQT--PAPPKLDVGFGGYG--AEGGEPGVY 337

  Fly   961 FARL 964
            :..|
Human   338 YQGL 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	39/75 (52%)
FOXA3	NP_004488.2	FH_FOXA3	115..216	CDD:410814	46/109 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..276		17/88 (19%)