DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CHES-1-like and Foxj3

DIOPT Version :9

Sequence 1:	NP_001259311.1	Gene:	CHES-1-like / 31678	FlyBaseID:	FBgn0029504	Length:	1268	Species:	Drosophila melanogaster
Sequence 2:	NP_001101441.1	Gene:	Foxj3 / 313554	RGDID:	1311770	Length:	622	Species:	Rattus norvegicus

Alignment Length:	559	Identity:	130/559 - (23%)
Similarity:	204/559 - (36%)	Gaps:	185/559 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   632 EDSLKEFDLVVSSRLHTSTPQYSVSKNGA--NGYGNGNSNVNGSGAGSNTPQKQKHPNNVPYDPL 694
            |.||...|.     |...|.:.::.|:.|  |.:|.|.|..|.. ...||...|:....
  Rat    21 ESSLTSMDW-----LPQLTMRAAIQKSDATQNAHGTGISKKNAL-LDPNTTLDQEEVQQ------ 73

  Fly   695 VHTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFV 759
             |.:.|||||::|||..||..|.:|.:.:.|||.||..:|||::.|.:|||||:||||||||.|:
  Rat    74 -HKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFL 137

  Fly   760 KVEKA-PNMGKGSLWRVEPQQRQNLIQALNRSPFFPNSAVDKISPSLKSPSGGSAYDSLDGGGSG 823
            ||.:: .:.||||.|.::...:::.:      |..|.    |.:.|::..|...:.|| |..|..
  Rat   138 KVPRSKDDPGKGSYWAIDTNPKEDTL------PTRPK----KRARSVERASTPYSIDS-DSLGME 191

  Fly   824 SVSSAQPVAGGAGVPAAAAVALSTPTKSNGLALANGASQATNAARPHSPNGGGSGSHARFDPYLF 888
            .:.|..         |:..:|::|               .||....::.:..||.|
  Rat   192 CIISGS---------ASPTLAINT---------------VTNKVTLYNTDQDGSDS--------- 223

  Fly   889 PNLSKAFRNIREDTVGQPMLQDALDDELSGDYHNNNNNNSGSKYNYMGANGSGGAGSGGVGSNAN 953
            |..|               |.::|.|:   ...:.|.|:.||.::|.           .|.::..
  Rat   224 PRSS---------------LNNSLSDQ---SLASVNLNSVGSVHSYT-----------PVTNHPE 259

  Fly   954 GASDGI----------------------NFARLARDCGADSIDDVHAAAAMLYLKHGPKIYSEPF 996
            ..|..:                      ||            :|:.|:...||    ..::.:..
  Rat   260 PVSQSLTPQQQPQYNLPERDKQLLFTEYNF------------EDLSASFRSLY----KSVFEQSL 308

  Fly   997 -QNGSGPVITSSPSEDHTYSAGGNSNADSGSSTPLTNGNALASVAQAVAQGQNNQGGAGSDSNCA 1060
             |.|...:.:.|..:.||..:..:|.:.:.:|.|.:|.::|          .||..|
  Rat   309 SQQGLMSIPSESSQQSHTSCSYQHSPSSTVTSHPHSNQSSL----------PNNHSG-------- 355

  Fly  1061 SSDAAYDSSEENHNITPEEMADRQRHRDGVDALLSLSGSSIVECGSVATTHYHSNGSSGS---SH 1122
                                             ||.:||:.|...|::....|:..|..:   .|
  Rat   356 ---------------------------------LSATGSNSVAQVSLSHPQMHTQPSPHTPHRPH 387

  Fly  1123 GSP-HKRASSHSLEEEHLQQHREQQLQQQQQQQQHHHQQ 1160
            |.| |.:...|  ...|.|||.:.|....|....|.|.|
  Rat   388 GLPQHPQRPQH--PASHPQQHSQLQPPHSQHPPPHQHIQ 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_001259311.1	Forkhead	700..785	CDD:278670	42/85 (49%)
Foxj3	NP_001101441.1	COG5025	<54..345	CDD:227358	92/387 (24%)
Foxj3	NP_001101441.1	FH_FOXJ3	77..155	CDD:410826	42/77 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010