Protein Alignment CHES-1-like and Foxg1

DIOPT Version :9

• Sequence 1: NP_001259311.1
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_036692.1
• Gene: Foxg1 / 24370
• RGDID: 2619
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 567
• Identity: 132/567 - (23%)
• Similarity: 197/567 - (34%)
• Gaps: 201/567 - (35%)

  Fly   461 VPKTSSF---STVFEAVNYATSAASNSSSSSNSTPNSQAILHGQESPAVVTTTTLISAGTLPPGY 522
            :|| |||   |.|.|||......||:...:|:...:.....|....|              ||
  Rat    13 IPK-SSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHPP--------------PP-- 60

  Fly   523 SFVNQVASTPHVLSTPAHVASPETPPGAALLPGTYYATSTTSAGTTTTTLQARSLQLSVSP--PP 585
                  |..|    .|......:.||.|...|                  |||....:...  |.
  Rat    61 ------APQP----PPPPPQQQQQPPPAPQPP------------------QARGAPAADDDKGPQ 97

  Fly   586 PNMTPTSQVHNGSLGGGGGGGGGSGGGGGGGGANLRSPNSYASYDNEDSLKEFDLVVSSRLHTST 650
            |.:.|.|...:|:.....|..|..|||          |...|....::..|
  Rat    98 PLLLPPSAALDGAKADALGAKGEPGGG----------PAELAPVGPDEKEK-------------- 138

  Fly   651 PQYSVSKNGANGYGNGNSNVNGSGAGSNTPQ--KQKHPNNVPYDPLVHTNNKPPYSFSSLIFMAI 713
                       |.|.|.....|:|.|....:  |:....|..|:       |||:|:::||.|||
  Rat   139 -----------GAGAGGEEKKGAGEGGKDGEGGKEGDKKNGKYE-------KPPFSYNALIMMAI 185

  Fly   714 EGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVKVEK-APNMGKGSLWRVEP 777
            ..|.||.|.:..||.:|:::|||::....||:||:||||||||.||||.: ..:.|||:.|.::|
  Rat   186 RQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDP 250

  Fly   778 --------------QQRQNLIQA-----------------LNR--SPFFPNSAVDKISP--SLKS 807
                          ::|....:|                 ::|  |.::|      :||  ||..
  Rat   251 SSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWP------MSPFLSLHH 309

  Fly   808 PSGGSAYDSLDGGGSGSVSSAQPVAGGAGVPAAAAVALSTPTKSNGLALANGAS--QATNAARPH 870
            |...|   :|...|:.|...:.|      :|.::.:..::...::..:.|||.|  :..|...|:
  Rat   310 PRASS---TLSYNGTTSAYPSHP------MPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPY 365

  Fly   871 S-------------PNGGG---SGSHARFDP-----------YLFPNL-----------SKAFRN 897
            :             |.|..   ||::: .:|           |.||::           |.:.|.
  Rat   366 ATHHLTAAALAASVPCGLSVPCSGTYS-LNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARA 429

  Fly   898 IREDTVGQ--------------PMLQDALDDELSGDYHNNNNNNSGS 930
            ....|..|              |.....|...|| ||..:.|..|.|
  Rat   430 ASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLS-DYFTHQNQGSSS 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_001259311.1	Forkhead	700..785	CDD:278670	41/99 (41%)
Foxg1	NP_036692.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..172		39/226 (17%)
		FH_FOXG	172..250	CDD:410795	39/77 (51%)
		COG5025	<175..>347	CDD:227358	53/186 (28%)
		Required for interaction with TLE6. /evidence=ECO:0000250|UniProtKB:Q60987	240..335		21/109 (19%)
		Interaction with KDM5B. /evidence=ECO:0000250	374..397		5/23 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..446		4/27 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910