Protein Alignment CHES-1-like and Foxc2

DIOPT Version :10

• Sequence 1: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_001095150.1
• Gene: Foxc2 / 171356
• RGDID: 621703
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 638
• Identity: 152/638 - (23%)
• Similarity: 209/638 - (32%)
• Gaps: 222/638 - (34%)

  Fly   652 QYSVSKNGANG----------------YG---------NGNSNVNGSGAG-SNTPQKQKHPNNVP 690
            :||||...|.|                ||         :|:....|:|.| |..|  ..|....|
  Rat     4 RYSVSDPNALGVVPYLSEQNYYRAAGSYGGMASPMGVYSGHPEQYGAGMGRSYAP--YHHQPAAP 66

  Fly   691 YDPLVHTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLN 755
            .| ||    |||||:.:||.|||:.:.||.:.:..||.:|:..||:::....||:||:|||||||
  Rat    67 KD-LV----KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLN 126

  Fly   756 KSFVKV---EKAPNMGKGSLWRVEPQQRQNLIQ---ALNRSPFFPNSAVDKISPS---LKSPSGG 811
            :.||||   :|.|  ||||.|.::|.. .|:.:   .|.|...|....|.|....   ||.|...
  Rat   127 ECFVKVPRDDKKP--GKGSYWTLDPDS-YNMFENGSFLRRRRRFKKKDVPKDKEERAHLKEPPPA 188

  Fly   812 SAYDSLDGGGSGSVSSAQPVAGGAGVP-----------AAAAVALSTPTKSNGLALANGASQATN 865
            ||    .|..:|:     |||.|   |           .||:.||...||...|: ..||.||:.
  Rat   189 SA----KGAPTGT-----PVADG---PKEAEKKVVVKSEAASPALPVITKVETLS-PEGALQASP 240

  Fly   866 AARPHSPNGGGSGS---HARFDPYLFPNLS-KAFRNIREDTVGQPMLQDALDDELSGDYHNNNNN 926
            .:...:|.|...||   |....|...|..| :....:|....|             ||.
  Rat   241 RSSASTPAGSPDGSLPEHHAAAPNGLPGFSVETIMTLRTSPPG-------------GDL------ 286

  Fly   927 NSGSKYNYMGANGSGGAGSGGVGSNANGASDGINFARLARDCGADSIDDVHAAAAMLYLKHGPKI 991
                         |..|...|:                           |....|:.|....|..
  Rat   287 -------------SPAAARAGL---------------------------VVPPLALPYAAAPPAA 311

  Fly   992 YSEPFQNGSGPVITSSPSEDHTYSAGGNSNADSGSSTPLTNGNALASVAQAVAQGQNNQGGAGSD 1056
            |::|                                               .|||....|.||..
  Rat   312 YAQP-----------------------------------------------CAQGLEAAGSAGYQ 329

  Fly  1057 SNCASSDAAYDSSEENHNITP----EEMADRQRHRDGVDALLSLSGSSIVECGSVATTHYHSNGS 1117
            .:..:......:....|...|    |.::|   |..|..:.|.....:..:.|::        |:
  Rat   330 CSMRAMSLYTGAERPAHVCVPPALDEALSD---HPSGPGSPLGALNLAAGQEGAL--------GA 383

  Fly  1118 SGSSHGSPHKRASSHSLEEEHLQQHREQQLQQQQQQQQHHHQQFGSSQAVYTNGSGSKMALLSSA 1182
            ||..|       ..||        |...|......|.....|....:.:.|.|..|.    ||..
  Rat   384 SGHHH-------QHHS--------HLHPQAPPPAPQPPPAPQPATQATSWYLNHGGD----LSHL 429

  Fly  1183 AANVALAQQQQQQIHQDMYSSTAGHNASMYLGGLNSHCLSGGGGVGVAAGMLP 1235
            ..:....|||.....::|::|   |..     ||::..| |...|..|:..||
  Rat   430 PGHTFATQQQTFPNVREMFNS---HRL-----GLDNSTL-GESQVSNASCQLP 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	39/77 (51%)
Foxc2	NP_001095150.1	FH_FOXC1	66..158	CDD:410818	45/99 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..213		15/58 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	233..267		10/33 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	380..422		11/64 (17%)