Protein Alignment CHES-1-like and Foxg1

DIOPT Version :9

• Sequence 1: NP_001259311.1
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_001153584.1
• Gene: Foxg1 / 15228
• MGIID: 1347464
• Length: 481
• Species: Mus musculus
• Alignment Length: 567
• Identity: 132/567 - (23%)
• Similarity: 197/567 - (34%)
• Gaps: 200/567 - (35%)

  Fly   461 VPKTSSF---STVFEAVNYATSAASNSSSSSNSTPNSQAILHGQESPAVVTTTTLISAGTLPPGY 522
            :|| |||   |.|.|||......||:...:|:...:.....|....|              ||
Mouse    13 IPK-SSFSINSLVPEAVQNDNHHASHGHHNSHHPQHHHHHHHHHHPP--------------PP-- 60

  Fly   523 SFVNQVASTPHVLSTPAHVASPETPPGAALLPGTYYATSTTSAGTTTTTLQARSLQLSVSP--PP 585
                  |..|   ..|......:.||.|...|                  |||....:...  |.
Mouse    61 ------APQP---PPPPPQQQQQQPPPAPQPP------------------QARGAPAADDDKGPQ 98

  Fly   586 PNMTPTSQVHNGSLGGGGGGGGGSGGGGGGGGANLRSPNSYASYDNEDSLKEFDLVVSSRLHTST 650
            |.:.|.|...:|:.....|..|..|||          |...|....::..|
Mouse    99 PLLLPPSTALDGAKADALGAKGEPGGG----------PAELAPVGPDEKEK-------------- 139

  Fly   651 PQYSVSKNGANGYGNGNSNVNGSGAGSNTPQ--KQKHPNNVPYDPLVHTNNKPPYSFSSLIFMAI 713
                       |.|.|.....|:|.|....:  |:....|..|:       |||:|:::||.|||
Mouse   140 -----------GAGAGGEEKKGAGEGGKDGEGGKEGDKKNGKYE-------KPPFSYNALIMMAI 186

  Fly   714 EGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVKVEK-APNMGKGSLWRVEP 777
            ..|.||.|.:..||.:|:::|||::....||:||:||||||||.||||.: ..:.|||:.|.::|
Mouse   187 RQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDP 251

  Fly   778 --------------QQRQNLIQA-----------------LNR--SPFFPNSAVDKISP--SLKS 807
                          ::|....:|                 ::|  |.::|      :||  ||..
Mouse   252 SSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWP------MSPFLSLHH 310

  Fly   808 PSGGSAYDSLDGGGSGSVSSAQPVAGGAGVPAAAAVALSTPTKSNGLALANGAS--QATNAARPH 870
            |...|   :|...|:.|...:.|      :|.::.:..::...::..:.|||.|  :..|...|:
Mouse   311 PRASS---TLSYNGTTSAYPSHP------MPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPY 366

  Fly   871 S-------------PNGGG---SGSHARFDP-----------YLFPNL-----------SKAFRN 897
            :             |.|..   ||::: .:|           |.||::           |.:.|.
Mouse   367 ATHHLTAAALAASVPCGLSVPCSGTYS-LNPCSVNLLAGQTSYFFPHVPHPSMTSQTSTSMSARA 430

  Fly   898 IREDTVGQ--------------PMLQDALDDELSGDYHNNNNNNSGS 930
            ....|..|              |.....|...|| ||..:.|..|.|
Mouse   431 ASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLS-DYFTHQNQGSSS 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_001259311.1	Forkhead	700..785	CDD:278670	41/99 (41%)
Foxg1	NP_001153584.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..173		39/226 (17%)
		FH	173..261	CDD:214627	40/87 (46%)
		Required for interaction with TLE6. /evidence=ECO:0000269|PubMed:16314515	241..336		21/109 (19%)
		Interaction with KDM5B. /evidence=ECO:0000250	375..398		5/23 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	419..447		4/27 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910