Protein Alignment CHES-1-like and Foxh1

DIOPT Version :10

• Sequence 1: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: NP_032015.1
• Gene: Foxh1 / 14106
• MGIID: 1347465
• Length: 401
• Species: Mus musculus
• Alignment Length: 303
• Identity: 80/303 - (26%)
• Similarity: 115/303 - (37%)
• Gaps: 85/303 - (28%)

  Fly   638 FDLVVSSRLHTSTPQYSVSKNGANGY-----GNGNSNVNGSGAG--SNTPQKQKHPNNVPYDPLV 695
            :||..:....|.:||.:::.  |.||     ...||.:....|.  |.||:::|...      |.
Mouse     5 WDLASTYTPTTPSPQLALAP--AQGYLPCMGPRDNSQLRPPEAESLSKTPKRRKKRY------LR 61

  Fly   696 HTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVK 760
            |  :||||::.::|.:.|:.:..:.|.:.:|...:...||:|:....|||:|:|||||.|:.|.|
Mouse    62 H--DKPPYTYLAMIALVIQAAPFRRLKLAQIIRQVQAVFPFFRDDYEGWKDSIRHNLSSNRCFHK 124

  Fly   761 VEKAP--NMGKGSLWRV-------EPQQRQNLI--------------------QALNRSPFFPNS 796
            |.|.|  ...||:.|.|       |..:.||..                    ..|:..|:.|
Mouse   125 VPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNRGTHRAFAKDLSPYVLHGQPYQP-- 187

  Fly   797 AVDKISPSLKSP--SGGSAYDSLDGGGSGSVSSAQPVAGGAGVP----AAAAVALST-------- 847
                  ||...|  .|.|....|...|..|.....|     |:|    ||.|..||.
Mouse   188 ------PSPPPPPREGFSIKSLLGDPGKESTWPQHP-----GLPGQSTAAQAGTLSKGEEGMGTG 241

  Fly   848 PTKSN-----------GLALANGASQATNAARPHSPNGGGSGS 879
            |:.|:           |..:..|.|......|| ||.....||
Mouse   242 PSSSSETPLWPLCSLPGPTIIEGESSQGEVIRP-SPVTPDQGS 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	29/76 (38%)
Foxh1	NP_032015.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	32..57		6/24 (25%)
		FH_FOXH	64..142	CDD:410796	29/77 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..251		21/84 (25%)
		SMAD-interaction domain (SID)	307..390
		Fast/FoxH1 motif 1 (FM1)	311..315
		Fast/FoxH1 motif 2 (FM2)	321..327
		SMAD interaction motif (SIM)	363..384