Protein Alignment CHES-1-like and FOXN4

DIOPT Version :10

• Sequence 1: NP_511071.3
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_011536224.1
• Gene: FOXN4 / 121643
• HGNCID: 21399
• Length: 518
• Species: Homo sapiens
• Alignment Length: 619
• Identity: 147/619 - (23%)
• Similarity: 213/619 - (34%)
• Gaps: 204/619 - (32%)

  Fly   483 NSSSSSNSTPNSQAIL---HGQESPAVVTTTTLISAGTLPPGYSFVNQVASTPHVLSTPAHVASP 544
            ||..:.:.:|....:|   ...:.|..:.:.:.::|..:|.    :.|:||....|..|   ..|
Human    16 NSGQNHHPSPQEYRLLATTSDDDLPGDLQSLSWLTAVDVPR----LQQMASGRVDLGGP---CVP 73

  Fly   545 ETPPGAALLPGTYYATSTTSAGTTTTTLQARSLQLSVSPPPPNMTPTSQVHNGSLGGGGGGG--- 606
            ...|||.             ||..       .|.:..:|.|....|......|..|.|...|
Human    74 HPHPGAL-------------AGVA-------DLHVGATPSPLLHGPAGMAPRGMPGLGPITGHRD 118

  Fly   607 --------GGSGGGGGGGGANLRSPNSYASYDNEDSLKEFDLVVSSRLHTSTPQYSVSKNGANGY 663
                    ||....|.....:|.||                        .:.||:.:........
Human   119 SQMSQFPVGGQPSSGLQDPPHLYSP------------------------ATQPQFPLPPGAQQCP 159

  Fly   664 GNGNSNVNGSGAGSNTPQKQK----------HPNNVPYDPLVHTNNKPPYSFSSLIFMAIEGSNE 718
            ..|   :.|...|...|..|.          ||.:.|         ||.||:|.||.||::.|..
Human   160 PVG---LYGPPFGVRPPYPQPHVAVHSSQELHPKHYP---------KPIYSYSCLIAMALKNSKT 212

  Fly   719 KALPVKEIYAWIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVKVEK--APNMGKGSLW-----RVE 776
            .:|||.|||:::.:|||||||||:||||||||||||||.|.|||.  :.:..||.||     |::
Human   213 GSLPVSEIYSFMKEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARID 277

  Fly   777 PQQ------RQNLIQALNRSPFFPNSAVDKI----SPSLKSPSGGSAYDSLDGGGSGSVSSAQPV 831
            ..:      ::..:.|::||...|.. :||:    ..|.:.|
Human   278 KMEEEMHKWKRKDLAAIHRSMANPEE-LDKLISDRPESCRRP----------------------- 318

  Fly   832 AGGAGVPAAAAVALSTPTKSNGLALANGASQAT------------------NAARPHSPNGGGSG 878
             |..|.|.|..:     |.:..:|:|:|....:                  :..:|.:.....|.
Human   319 -GKPGEPEAPVL-----THATTVAVAHGCLAVSQLPPQPLMTLSLQSVPLHHQVQPQAHLAPDSP 377

  Fly   879 SHARFDP-YLFPNLSKA-------------FRNIREDTVGQPMLQDALDDELSGDYHNNNN---- 925
            :.|:..| :..|:||.:             |.||..|...:   .||||..:. |:....|
Human   378 APAQTPPLHALPDLSPSPLPHPAMGRAPVDFINISTDMNTE---VDALDPSIM-DFALQGNLWEE 438

  Fly   926 -NNSGSKYNYMGANGSG--GAGSGGVG-SNANGASDGINFARLARDCGADSIDDVHAAAAMLYLK 986
             .:.|...:.:||....  |...|..| :.|:|.||             .|..|:....  ||
Human   439 MKDEGFSLDTLGAFADSPLGCDLGASGLTPASGGSD-------------QSFPDLQVTG--LY-- 486

  Fly   987 HGPKIYSEPFQNGSGPVITSSPSEDHTY-SAGGN 1019
               ..||.|     ..|..|..|....| .|.||
Human   487 ---TAYSTP-----DSVAASGTSSSSQYLGAQGN 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_511071.3	FH_FOXN2-like	700..775	CDD:410805	47/81 (58%)
FOXN4	XP_011536224.1	PABP-1234	<56..219	CDD:130689	48/225 (21%)
		FH_FOXN4	189..294	CDD:410831	50/113 (44%)
		FAM75	318..>398	CDD:464237	16/108 (15%)