Protein Alignment CHES-1-like and Foxp2

DIOPT Version :9

• Sequence 1: NP_001259311.1
• Gene: CHES-1-like / 31678
• FlyBaseID: FBgn0029504
• Length: 1268
• Species: Drosophila melanogaster
• Sequence 2: XP_036021645.1
• Gene: Foxp2 / 114142
• MGIID: 2148705
• Length: 740
• Species: Mus musculus
• Alignment Length: 686
• Identity: 170/686 - (24%)
• Similarity: 252/686 - (36%)
• Gaps: 249/686 - (36%)

  Fly   279 QQQQNSPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ---------------------------- 315
            ||||...||||||||||||||||||||||||||||||
Mouse   180 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQ 244

  Fly   316 --------QQTTYLPTPTRTTMV----GHGYMPVVVSSASQPILSPAK-QQLPQQI----YVTSN 363
                    ||..:|.:..|..::    |...:|  |.|..|..||||: |||.:::    .:..|
Mouse   245 QLLQMQQLQQQQHLLSLQRQGLISIPPGQAALP--VQSLPQAGLSPAEIQQLWKEVTGVHSMEDN 307

  Fly   364 GSSPAGGGTIYKAASQALSSPTTSSSSSSNTTTHHPHKKYLREKMHVQMDHSSHVASTVTVVSSP 428
            |....|           |...|.:|||::::||         .|....:.|.|       :|:..
Mouse   308 GIKHGG-----------LDLTTNNSSSTTSSTT---------SKASPPITHHS-------IVNGQ 345

  Fly   429 ASSNNSSISSSNTGSVSGSGSSTAAVNGGNSPVPKTSS----FSTVFEAVNYATSAASNSSSS-- 487
            :|..|:...||   |...:|:|......|....|...|    |....:.:|...:....|::.
Mouse   346 SSVLNARRDSS---SHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCR 407

  Fly   488 -------------SNSTPNSQAI---LH---GQESPAVVTTTTLISAGTLPPGYSFVNQVASTPH 533
                         |......||:   ||   .:..|:             |...:.|:.|..:.:
Mouse   408 VQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPS-------------PKPLNLVSSVTMSKN 459

  Fly   534 VLSTPAHVASPETPPGAALLPGTYYATSTTSAGTTTTTLQARSLQLSVSPPPPNMTPTSQVHNGS 598
            :|.|     ||::.|          .|.||.....|...|.          |..:||.|..:.|:
Mouse   460 MLET-----SPQSLP----------QTPTTPTAPVTPITQG----------PSVITPASVPNVGA 499

  Fly   599 LGGGGGGGGGSGGGGGGGGANLRSPNSYASYDNEDSLKEFDLVVSSRLHTSTPQYSVSKNGANGY 663
                                 :|..:|          .::::.:||.:   .|.|...||
Mouse   500 ---------------------IRRRHS----------DKYNIPMSSEI---APNYEFYKN----- 525

  Fly   664 GNGNSNVNGSGAGSNTPQKQKHPNNVPYDPLVHTNNKPPYSFSSLIFMAIEGSNEKALPVKEIYA 728
                                             .:.:||:::::||..||..|:::.|.:.|||:
Mouse   526 ---------------------------------ADVRPPFTYATLIRQAIMESSDRQLTLNEIYS 557

  Fly   729 WIVQHFPYFKTAPNGWKNSVRHNLSLNKSFVKVEKAPNMGKGSLW---RVEPQQRQNLIQALNRS 790
            |..:.|.||:.....|||:|||||||:|.||:||..    ||::|   .||.|:|::  |.:..|
Mouse   558 WFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENV----KGAVWTVDEVEYQKRRS--QKITGS 616

  Fly   791 PFFPNSAVDKISPSLKSPSGGSAYDSLDGGGSGSVSSAQPVAGGAGVPAAAAVALSTP----TKS 851
            |    :.|..|..||             |.|:...:|.|.....:.:|     .||.|    ..|
Mouse   617 P----TLVKNIPTSL-------------GYGAALNASLQAALAESSLP-----LLSNPGLINNAS 659

  Fly   852 NGLALANGASQATNAARPHSPNGGGSGSHARFDPYL 887
            :||..|  ..:..|.:..|..:.|.|.......|::
Mouse   660 SGLLQA--VHEDLNGSLDHIDSNGNSSPGCSPQPHI 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHES-1-like	NP_001259311.1	Forkhead	700..785	CDD:278670	37/87 (43%)
Foxp2	XP_036021645.1	FOXP-CC	367..434	CDD:406546	9/66 (14%)
		COG5025	502..>733	CDD:227358	68/273 (25%)
		FH_FOXP2	528..609	CDD:410839	36/84 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	118	1.000	Inparanoid score	I4780
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050