DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and slc5a6b

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	XP_005158632.1	Gene:	slc5a6b / 796312	ZFINID:	ZDB-GENE-050913-86	Length:	603	Species:	Danio rerio

Alignment Length:	571	Identity:	182/571 - (31%)
Similarity:	309/571 - (54%)	Gaps:	48/571 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPITMSLISSF 81
            ||::|.|:|.....||:|:..           .|..:  |:...:|:..|.||..|:::||:::|
Zfish    13 DYVIFGLLLVASMSIGLYYAF-----------TGGRQ--STTQEFLIADRSMKCLPLSLSLMATF 64

  Fly    82 ISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRYNRSLRLF 146
            .|.:.::|||.|||.:|.||.:|..|.||......:.|:|:|:.|:|.|.|:|||.|:.:::|:.
Zfish    65 QSAVAIIGTPAEVYAHGTQYWFIGCSYVLGLLIPAHIFIPLFYRLHLTSVYQYLELRFCKAVRIC 129

  Fly   147 GSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQTLI 211
            |:|.||...::::.:.||.||:|.|..||.::........:||..||.:|||||||||||.||::
Zfish   130 GTVTFIFQMVIYMGVGIYTPALALNAVTGFHLWGAVLATGLVCTLYTALGGLKAVVWTDVFQTVV 194

  Fly   212 MFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVLGGVAHWLKSNAIS 276
            ||.....|:|.|....||....|.|.::..|:...:.:.|.:.|:||::|.:|||...|....::
Zfish   195 MFTGQLAVIIVGVHQAGGLSEAWGKVRDGGRISGIDLNPDPTVRHTFWTLAVGGVFLMLSLYGVN 259

  Fly   277 QNMIQRYLSLPTLRDARIAIW-TFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLAQRNDQLLP 340
            |..:|||||..|.|:|.::.: .|....||.|:.| ..||:::|.|.|..|:|.:.....||::.
Zfish   260 QAQVQRYLSSRTEREAVMSCYMVFPCLQLALLLSC-LMGLVMFACYGQNSPVEQQYITSKDQMVL 323

  Fly   341 LLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVMRSV 405
            ..|||.|.::|||||:|||.:|||:||::|:..|||:.|.:.|.:|....  :||.:...:.:.:
Zfish   324 YFVMDMLQNFPGLPGLFVACLFSASLSTISSAFNSLATVTMVDLIKPHYS--MTEARATLLSKLL 386

  Fly   406 VVVFGIIFVALVFAVEKL-GAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLGGFSSLIV 469
            .:.:|||.:|:.:.|..: .:|||..:::..:..|||||:|..|:..|..||.||:.|..:.|::
Zfish   387 ALSYGIICLAMAYLVHLMNSSVLQAALSIFGMIGGPLLGLFCLGIFFPCANSIGAVTGLSAGLLM 451

  Fly   470 MAWMCVSAQRDLVTGDLVYKRKPYSTMGCNYTFAGEPREFASLALDGAISSVPSAPFQL------ 528
            ..|:.:.       |.|.  |.|...:         |...:::.:.....::.:|..:|
Zfish   452 AFWVGIG-------GFLT--RMPSPVI---------PLLNSTITVPDVSENITAATAELEADSRS 498

  Fly   529 ------YRISYLYFTLFGALVTIVVALVTSLLLRETDLDGVDTRLLTPFVR 573
                  |.:||::::...:...::|.|:.|.:...|..|.|.:..:.|.|:
Zfish   499 AGLHGFYSLSYMWYSALSSCTVLIVGLIISCITGPTKGDDVASGTVYPVVK 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	177/550 (32%)
slc5a6b	XP_005158632.1	SLC5-6-like_sbd	9..532	CDD:294310	177/552 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820