Protein Alignment CG9657 and SLC5A3

DIOPT Version :9

• Sequence 1: NP_001284983.1
• Gene: CG9657 / 31674
• FlyBaseID: FBgn0029950
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_008864.4
• Gene: SLC5A3 / 6526
• HGNCID: 11038
• Length: 718
• Species: Homo sapiens
• Alignment Length: 598
• Identity: 135/598 - (22%)
• Similarity: 243/598 - (40%)
• Gaps: 150/598 - (25%)

  Fly    29 AVIGIYFCLQLRLE-SRKQKANGSEEAASSAASYLVGGRQMKIFPITMSLISSFISG---ITLLG 89
            |::.:||.|.:.:. ....|:|     .|:.:.|.:.||.|....|..||..|.|..   |.|.|
Human    11 AIVALYFILVMCIGFFAMWKSN-----RSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFIGLAG 70

  Fly    90 TPTEVYLYGAQYMYIMGS--------LVLMGFCMYYFFLPVFHELNLISTYKYLEQRY--NRSLR 144
            :       ||...:.:|:        |.|:|    :.|:|::....:.:..:||.:|:  :|...
Human    71 S-------GAASGFAVGAWEFNALLLLQLLG----WVFIPIYIRSGVYTMPEYLSKRFGGHRIQV 124

  Fly   145 LFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQT 209
            .|.::..|:.....|.:.:|..|:...::.|.|:::...::..:....|..|||.||::||.:|.
Human   125 YFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQA 189

  Fly   210 LIM-FGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADL--------------------- 252
            |:| .||:.|::| ..::|||    :::.:....|..|:.::.|
Human   190 LLMIIGALTLMII-SIMEIGG----FEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEALK 249

  Fly   253 ------SERYTFYSLVLG----GVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFL 307
                  .|...:...:||    .|.:|    ...|.::||.|:...:..|:.:  |.:||.|..|
Human   250 MLRNPTDEDVPWPGFILGQTPASVWYW----CADQVIVQRVLAAKNIAHAKGS--TLMAGFLKLL 308

  Fly   308 -----MICGYTGLLIYATYSQC-DPLETKL-----AQRNDQLLPLLVMDTLGSYP-GLPGVFVAG 360
                 ::.|....:::.....| :|....|     |..::...|.|||..:   | ||.|:.:|.
Human   309 PMFIIVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLV---PVGLRGLMMAV 370

  Fly   361 VFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVMRSVVVVFGIIFVALV-------- 417
            :.:|.:|.|.:..||.|.:...|..|..|||..:        |.:::| |.||||.:
Human   371 MIAALMSDLDSIFNSASTIFTLDVYKLIRKSASS--------RELMIV-GRIFVAFMVVISIAWV 426

  Fly   418 -FAVEKLGAVLQLTITLSSVAN---GPLLGIFTAGVMLPWVNSKGALLGGFSSLIVMAWMCVSAQ 478
             ..||..|.  |:.:.:..||:   .|:..:|...:.....|.:||..||.:..::.|...:.|
Human   427 PIIVEMQGG--QMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVLGAVRLILA- 488

  Fly   479 RDLVTGDLVYKRKPYSTMGCNYTFAGEPREFASLALDGAISSVPSAPFQLYRISYLY-----FTL 538
                        ..|....|:     :|               .:.|..:..|.|:|     |.:
Human   489 ------------FAYRAPECD-----QP---------------DNRPGFIKDIHYMYVATGLFWV 521

  Fly   539 FGALVTIVVALVT 551
            .| |:|::|:|:|
Human   522 TG-LITVIVSLLT 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	135/598 (23%)
SLC5A3	NP_008864.4	SLC5sbd_SMIT	9..718	CDD:271382	135/598 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146490
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740