DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and slc5a5

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001082860.1	Gene:	slc5a5 / 561445	ZFINID:	ZDB-GENE-060503-585	Length:	601	Species:	Danio rerio

Alignment Length:	571	Identity:	195/571 - (34%)
Similarity:	307/571 - (53%)	Gaps:	36/571 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPITMSLISSF 81
            ||.||..||.:...||::..|        :|..|    .|...|:..|||.....|:.:||.:||
Zfish    15 DYAVFAAMLGVSVGIGLFQSL--------RKTPG----RSKVDSFFTGGRGFSAVPVGLSLCASF 67

  Fly    82 ISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRYNRSLRLF 146
            :|.:.:||.|:|.||||.:::|:.....|........|:|||:.|.:.|:.:||..|:.|.::|.
Zfish    68 MSAVQVLGVPSETYLYGFKFLYMCLGQGLNSLMTAVLFVPVFYRLKITSSSQYLGMRFGRGMQLL 132

  Fly   147 GSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQTLI 211
            ||:.||||:||:..|||:.||:..|||||:|:........::|.|||.:||:|||:||||.|.::
Zfish   133 GSLQFIVATLLYTGIVIFAPAVILNQATGLNMWASLFSTGLICTFYTTVGGMKAVIWTDVFQIVV 197

  Fly   212 MFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVLGGVAHWLKSNAIS 276
            |......|.|:||:..|||..|.:.|...:|:...:|:.|...||:|:|..:||...||.....:
Zfish   198 MLSGFIAVFIQGTILAGGPARVLEIANNGSRINFNDFAIDPQRRYSFWSFTVGGTMVWLSMYGAN 262

  Fly   277 QNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLAQRNDQLLPL 341
            |..:|||:|..|.:.|::|:.....|:...:......|::::|.||.||||:.......||.:|.
Zfish   263 QAQVQRYISCRTEKQAQLALLVNQVGLCLIVSSAATCGIVMFALYSNCDPLKIGRISAPDQYMPY 327

  Fly   342 LVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVMRSVV 406
            ||:|...::||.||:|:|..:|..||::||.:|:::||.:||.:|.:..: :::.:...:.|::.
Zfish   328 LVLDIFRNHPGFPGLFLACAYSGTLSTVSTSINAMAAVTMEDVMKPWLIT-ISQRKQLMLSRALS 391

  Fly   407 VVFGI--IFVALVFAVEKLGAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLGGFSSLIV 469
            :.:|:  |.:|.:.::...| |||.:.|:..|.||||||.|..|:.:|..|..|...|......:
Zfish   392 LFYGLGCITMAALSSLLDWG-VLQGSFTVMGVVNGPLLGAFALGMFVPATNKPGVFSGVAVGFCL 455

  Fly   470 MAWMCVSAQRDLVTGDLVYKRKPYSTMGCNYTFAGE-PREFASLALDGAI--SSVP-SAPFQ-LY 529
            ..|:.|        |..:|...| ..||...|.||: ....|:|....::  |||| ...|| :|
Zfish   456 SLWLAV--------GSTIYPPSP-QIMGVLPTSAGQCLTTNATLNTTASVLASSVPLDYSFQNIY 511

  Fly   530 RISYLYFTLFGALVTIVVALVTSLLLRETDLDGVDTRLLTPFVRRW-LERR 579
            .||||||........::|.:|.|.:...|..|.:...||     || ||::
Zfish   512 SISYLYFGALSTSAVVLVGVVVSYITGPTKKDSISPGLL-----RWNLEQK 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	187/543 (34%)
slc5a5	NP_001082860.1	SLC5-6-like_sbd	14..549	CDD:320982	189/556 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580099
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950