DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and Slc5a8

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001178916.1	Gene:	Slc5a8 / 500820	RGDID:	1564146	Length:	611	Species:	Rattus norvegicus

Alignment Length:	578	Identity:	206/578 - (35%)
Similarity:	326/578 - (56%)	Gaps:	70/578 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 WPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPITMSLIS 79
            | ||:||..||.|.|.||||:..          |.|.::   ::..:|:|||.|...|:.:||.:
  Rat    13 W-DYVVFAGMLLISAAIGIYYAF----------AGGGQQ---TSKDFLMGGRSMSAVPVALSLTA 63

  Fly    80 SFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYF--------FLPVFHELNLISTYKYLE 136
            ||:|.:|:||||.|||.:||.:. |.|       ..|:|        |||||:.|.:.|||:|||
  Rat    64 SFMSAVTVLGTPAEVYRFGAIFS-IFG-------VTYFFVVVISAEVFLPVFYRLGITSTYEYLE 120

  Fly   137 QRYNRSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAV 201
            .|:||.:||.|:|:|||.::|:..||||.||:|.||.||.::........|||.||..:||||||
  Rat   121 LRFNRFIRLCGTVLFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAV 185

  Fly   202 VWTDVIQTLIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVLGGV 266
            |||||.|..||....|.|:|:.::..||...:...|....||...||:.:..:|:||:::::||.
  Rat   186 VWTDVFQVGIMVAGFASVIIQASITQGGINTILSDASNGGRLNFWNFNPNPLQRHTFWTIIVGGT 250

  Fly   267 AHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLETKL 331
            ..|.....::|:.:|||:|..:...|:::::..:.|:...|:...:.||.:|:.|..|||..:|.
  Rat   251 FTWTTIYGVNQSQVQRYISCKSRLHAKLSLYVNLVGLWVILICSVFCGLALYSRYHDCDPWTSKK 315

  Fly   332 AQRNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEG 396
            ....|||:|.||:|.|.:|||:||:|||..:|..||::|:.:|:|:||.:||.:|...|| |:|.
  Rat   316 VSEVDQLMPYLVLDILKNYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRFKS-LSEK 379

  Fly   397 QTAFVMRSVVVVFGIIFVALVFAVEKLGAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALL 461
            ..:::.:.:.|::|.:.:.:......:||:||..:::..:..|||||:|:.|:::|:.||.||..
  Rat   380 SLSWISQGMSVLYGALCIGMAAVASLMGALLQAALSIFGMVGGPLLGLFSLGILVPFANSVGAFA 444

  Fly   462 GGFSSLIVMAWMCVSAQRDLVTGDLVYKRKPYSTM-------GCNYTFAGEPREFASLALDGAIS 519
            |..:...|..|:.:.||        :|...|..|:       |||.|..|  .::.|      .:
  Rat   445 GLLAGFAVSLWVGIGAQ--------LYPPLPERTLPLSLETHGCNSTHNG--TDWMS------TT 493

  Fly   520 SVP--SAPFQL------------YRISYLYFTLFGALVTIVVALVTSLLL--RETDLD 561
            .:|  ::.||:            |.:|||||:..|.|.|::|.::.||..  |:.:||
  Rat   494 EMPFSTSAFQIHDVERSALMDNWYSLSYLYFSTIGTLTTLLVGILISLATGGRKQNLD 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	201/566 (36%)
Slc5a8	NP_001178916.1	SLC5sbd_SMCT1	7..549	CDD:271402	204/574 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340269
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.850