DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and CG42235

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_651446.2	Gene:	CG42235 / 43136	FlyBaseID:	FBgn0250757	Length:	698	Species:	Drosophila melanogaster

Alignment Length:	613	Identity:	263/613 - (42%)
Similarity:	395/613 - (64%)	Gaps:	23/613 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MHVEELRASLQSFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANG---------SEEAAS 56
            :.|::|..:||.||..|||||..|||:|||||.||.. :..:.:|||..|         .|...|
  Fly    90 LSVKDLSQALQHFGIVDYLVFIAMLAVCAVIGFYFGF-IEKKQKKQKLAGKDGGGAAGVEERRGS 153

  Fly    57 SAASYLVGGRQMKIFPITMSLISSFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLP 121
            .|..|||||||||:||:.:||::||:|||:||||.||:|:||.||.:|:.:|.:.|...:|.|||
  Fly   154 EALDYLVGGRQMKVFPVALSLVASFVSGISLLGTSTEIYVYGTQYAFILVTLAISGAISWYIFLP 218

  Fly   122 VFHELNLISTYKYLEQRYNRSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVC 186
            ||..|.|.|||:|.|:|::|.:|:|||.:|:|.::||.||.|||||:..||.:|:::..:.|:..
  Fly   219 VFCNLQLTSTYEYFERRFDRRVRIFGSCLFVVMNILWQPICIYVPALTLNQVSGISVSKIVPVTS 283

  Fly   187 VVCIFYTCIGGLKAVVWTDVIQTLIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSAD 251
            .:||.||.:||:|.||||||||..:|.|:|.:|:||||||:||..||....::..||..|:.:.|
  Fly   284 FICILYTSVGGIKGVVWTDVIQGTVMIGSMLIVIIKGTLDLGGLSVVLDHNRQYDRLVGPDMTFD 348

  Fly   252 LSERYTFYSLVLGGVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLL 316
            .:.|...::|.:||....|::|.|:|.::||||:||..:|.:.|:...:.|.:..:::|.|.|||
  Fly   349 PTARMGVFALFVGGALFKLQANGINQAIVQRYLTLPNNKDVKKALVLSLIGFMFVMLMCVYIGLL 413

  Fly   317 IYATYSQCDPLETKLAQRNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVL 381
            .:|.:..|||:.|.||:..||::||.|:..:|..|||.|:|||||||||||||||.|||||.|:|
  Fly   414 AFAEFYHCDPITTGLARAKDQVIPLYVVKNVGHIPGLVGLFVAGVFSAALSSLSTALNSLSGVIL 478

  Fly   382 EDFVKTFRKSPLTEGQTAFVMRSVVVVFGIIFVALVFAVEKLGAVLQLTITLSSVANGPLLGIFT 446
            .|||:.|||.||||.|||:::|.||:.||:|.:|.|..|::||.|:||:.|::::..|||||.|:
  Fly   479 TDFVEPFRKKPLTERQTAYLLRGVVISFGLISMASVPIVQRLGLVMQLSSTVAAITCGPLLGAFS 543

  Fly   447 AGVMLPWVNSKGALLGGFSSLIVMAWMCVSAQRDLVTGDLVYKRKPYSTMGCNYTFAGEPREFAS 511
            .|::||:|.::..|.|...:....|::.|.||..:.||.|.:..||.|...|:||| ..|..:
  Fly   544 VGMLLPFVKTESLLTGISCASSFTAYIVVRAQIAIFTGSLTFPAKPVSIQDCDYTF-DLPANW-- 605

  Fly   512 LALDGAISSVP--SAPFQLYRISYLYFTLFGALVTIVVALVTSLLLRETDLDGVDTRLLTPFVRR 574
               :...::.|  |....::.||:|::|..|::.|::.:|:.:|.....|...||..|::|.:|:
  Fly   606 ---NATTTATPTESTSHGIHEISFLWYTAVGSVGTVLGSLLATLYFGRQDPRVVDKELISPVLRK 667

  Fly   575 -WLERRRHRRSKIPDSGQKSSNKQETKT 601
             |.    .:...:....:.:.|..|::|
  Fly   668 FWY----GKYESVASEEKNNFNLHESET 691

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	246/548 (45%)
CG42235	NP_651446.2	SLC5sbd_NIS-SMVT	105..646	CDD:271383	246/547 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445293
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
	10	9.900