DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and CG7720

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001163649.1	Gene:	CG7720 / 42257	FlyBaseID:	FBgn0038652	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	630	Identity:	194/630 - (30%)
Similarity:	317/630 - (50%)	Gaps:	63/630 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LQSFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPIT 74
            |.:.|| |||:|.|.:|: .|:|   .|..|:..:|::        .|.|.|:.....:.|..:.
  Fly     5 LSTMGW-DYLMFVLFIAL-TVLG---PLWKRIFGKKKE--------RSKADYVFATGGVSIVAVM 56

  Fly    75 MSLISSFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRY 139
            :|:....:...::||.|:|:|..|:....|:..::.....:.:.|:||:..|.:.|.|:|::.|:
  Fly    57 ISIARGTLGVRSVLGYPSELYYRGSAMWEIIYGMMSAYPIVCFMFVPVYFNLGITSVYQYIDLRF 121

  Fly   140 -NRSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVW 203
             :|::|...|..:||..:..|.|.:|.|::|.:...|:........:.|:|||:|.:|||||.:.
  Fly   122 KSRTVRCLASATYIVRQICNLGITVYTPSVALSTVIGIPYWASITGMAVICIFFTIMGGLKAAIN 186

  Fly   204 TDVIQTLIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVLGGVAH 268
            .|||||:.:......|.|:||:..||...|:|..::..||...||:.|::.|....|..||.:..
  Fly   187 ADVIQTVTILVVTVAVCIQGTISTGGVKKVYQLNRDNGRLNFWNFTGDMTVRVDTTSAWLGQLFM 251

  Fly   269 WLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLAQ 333
            .|......||.:|||:||.:|:..|..:.|.:..|..|..|...:|::||:||..|||......:
  Fly   252 SLSQIGCQQNFMQRYVSLKSLKQVRRVMLTNVPLVFFFFSISWISGMVIYSTYINCDPYAEGYIK 316

  Fly   334 RNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRK-SPLTEGQ 397
            :.|::||..|.|.||..||..|:|:|.:|:.||..:.:.||||:.|:.|||:....| ..|::.|
  Fly   317 KPDEILPFFVEDQLGFLPGFVGIFMATLFNGALCMMVSNLNSLATVIWEDFISQLPKFKGLSDKQ 381

  Fly   398 TAFVMRSVVVVFGIIFVALVFAVEKLGAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLG 462
            ...:::|:.||.|:|.:.:.|.|..|..|::.::.:.|..:|||||.|...:|:|..|.||...|
  Fly   382 QLRILKSITVVCGLIIMGVAFGVGLLAGVIESSLLVFSATSGPLLGCFILAMMVPIANWKGTSAG 446

  Fly   463 GFSSLIVMAW-----MCVSAQRDLVTGDLVYKRKPYSTMGC-NYTFA----------GE-PREFA 510
            ..::...:.|     |.|:....|:         |.||.|| |.|||          |: |...:
  Fly   447 MVTACAFVLWIIGGGMTVTKDNPLL---------PTSTDGCTNDTFAQSIGKPIVEQGQMPWLLS 502

  Fly   511 SLALDGAISS-VPSAPF---------QLYRISYLYFTLFGALVTIVVALVTSLLLRETDLDGVDT 565
            ...:||...| ||:.|.         ..|.||::|::|.|..:|:::..|.|||.:..| |..|.
  Fly   503 HTPIDGFNQSFVPTQPTIAPERSGLETFYSISFMYYSLIGTALTVIIGTVISLLTQHPD-DAYDG 566

  Fly   566 RLLTPFVRRWLER---------RRHRRSKIPDSGQKSSNKQETKT 601
            :||.|.:.|..||         :....|.:  :|:.||:...|.|
  Fly   567 KLLHPLIFRLCERFSGRKPYYVKHEEESGL--NGRSSSDSSATTT 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	174/566 (31%)
CG7720	NP_001163649.1	SLC5sbd_NIS-SMVT	10..556	CDD:271383	175/567 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I2508
eggNOG	1	0.900	-	-		E1_COG0591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I307
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9745
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970