Protein Alignment rumpel and Gm5134

DIOPT Version :10

• Sequence 1: NP_572397.1
• Gene: rumpel / 31674
• FlyBaseID: FBgn0029950
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_006513854.1
• Gene: Gm5134 / 333669
• MGIID: 3646667
• Length: 695
• Species: Mus musculus
• Alignment Length: 608
• Identity: 133/608 - (21%)
• Similarity: 232/608 - (38%)
• Gaps: 166/608 - (27%)

  Fly    19 LVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPITMSLISSFI- 82
            :.|.|:|.:|  :|::..|              ..:..:...:.:.|:.:..:.:.:|:.||.|
Mouse    30 MTFYLLLVVC--VGLWALL--------------SHSRGTVKDFFLAGQNLAWWLMGISIYSSNIG 78

  Fly    83 SG--ITLLGTPTEVYLYGAQYMYIMGSL----VLMGFCMYYFFLPVFHELNLISTYKYLEQRYNR 141
            ||  :.|.|       .||.....:|:|    :.|.|.:.:.|:|::.:..:::..:||::|:.
Mouse    79 SGHYMALAG-------IGAASGIAVGALEWNSIFMLFLLGWIFVPIYSKAEVVTLPEYLKKRFG- 135

  Fly   142 SLR--LFGSVMFIVASLL-WLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVW 203
            |||  ||.:.:|::..:. .:.:.|...|:........:|:.....|..:...||..|||..|.:
Mouse   136 SLRIQLFFTFIFLIVYIFSRISMEIGFGAMFLKMVWDTDIYQTMLTVLTIIGMYTITGGLATVAY 200

  Fly   204 TDVIQTLIMFGAMALVLIKGTLDIGG-PGVV----------WQKAQETARLE--VPN------FS 249
            .:.:|..||....||::.....::|| |.:|          .|:...||:.|  :|.      |.
Mouse   201 VESLQAGIMILGSALLMGYAFYEVGGYPKLVSKYMEAIPSKTQQGNWTAQPECYLPRQDAFHIFR 265

  Fly   250 ADLSERYTFYSLVLGGVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLM-----I 309
            :.:|....:..|:||.....|......|..:||                |:||.....|     :
Mouse   266 SCVSGDIPWPGLILGATTVSLFYGCADQVSVQR----------------FLAGKSRLHMEGGCLL 314

  Fly   310 CGYTGLL--------------IY------ATYSQCDPLETKLAQRNDQLLPLLVMDTLGSYP-GL 353
            |||..||              :|      ...|:|.....:....:....|:||   ||..| ||
Mouse   315 CGYLKLLPMFLMVMPGMISRILYPDQVACVVPSECQKFCGRGTGCSALAYPVLV---LGVMPHGL 376

  Fly   354 PGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVMRSVVVVFGIIFVALVF 418
            .|..::.|.::.:|||::..||.||:...: :.|:.:...||.:        :::.|..||.::.
Mouse   377 QGFMLSTVCASLMSSLTSIFNSSSALFTLN-IYTWIRPTATEKE--------LMIAGRFFVIILL 432

  Fly   419 AV-------------EKLGAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLGGFSSLIVM 470
            ||             |.|...:|:   |.|.....:..:|...|....||.:||..|
Mouse   433 AVTIVWIPIIEMAPNEILFEYMQV---LKSCLTPSMTAVFLLAVFCKRVNEQGAFWG-------- 486

  Fly   471 AWMCVSAQRDLVTGDL--VYKRKP---YSTMGCNYTFAGEPREFASLALDGAISSVPSAPFQLYR 530
                      |:.|..  |::...   |..:.|     |..|:               .|..:..
Mouse   487 ----------LIVGTTIGVFRLLAEFFYGPVTC-----GRDRQ---------------CPIFICG 521

  Fly   531 ISYLYFTLFGALVTIVVALVTSL 553
            :.||||.....||||::.|..||
Mouse   522 LHYLYFGFCLFLVTILIILAISL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rumpel	NP_572397.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	133/608 (22%)
Gm5134	XP_006513854.1	SLC5-6-like_sbd	26..695	CDD:444915	133/608 (22%)