DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and Slc5a6

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001171092.1	Gene:	Slc5a6 / 330064	MGIID:	2660847	Length:	634	Species:	Mus musculus

Alignment Length:	577	Identity:	184/577 - (31%)
Similarity:	302/577 - (52%)	Gaps:	53/577 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SLQSFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPI 73
            ::.:|...||:||.|:|.:..|||:|...         :..|..    :....|:..|:|...|:
Mouse    19 AISTFSVVDYVVFGLLLVLSLVIGLYHAC---------RGWGHH----TVGELLMADRKMGCLPV 70

  Fly    74 TMSLISSFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQR 138
            .:||:::|.|.:.:||.|.|::.:|.||.::..|..|......:.|:|||:.|:|.|.|:|||.|
Mouse    71 ALSLLATFQSAVAILGAPAEIFRFGTQYWFLGCSYFLGLLIPAHIFIPVFYRLHLTSAYEYLELR 135

  Fly   139 YNRSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVW 203
            :|:::|:.|:|.||...::::.:.:|.|::|.|..||.::.:....:.:||..||.:||||||:|
Mouse   136 FNKAVRICGTVTFIFQMVIYMGVALYAPSLALNAVTGFDLWLSVLALGIVCNIYTALGGLKAVIW 200

  Fly   204 TDVIQTLIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVLGGVAH 268
            |||.|||:||....:|:|.|...:||.|.||....:...:...|...|...|:||::|..|||..
Mouse   201 TDVFQTLVMFLGQLVVIIVGAARVGGLGHVWNVTSQHGLISGINLDPDPFVRHTFWTLAFGGVFM 265

  Fly   269 WLKSNAISQNMIQRYLSLPTLRDARIAIW-TFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLA 332
            .|....::|..:|||||..:.|.|.::.: .|....:|..|.| ..||:::|.|:... :..:|.
Mouse   266 MLSLYGVNQAQVQRYLSSHSERAAVLSCYAVFPCQQVALCMSC-LIGLVMFAYYNMYS-MSPELK 328

  Fly   333 Q-RNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEG 396
            | ..|||:...|||.|...|||||:|||.:||.:||::|:..|||:.|.:||.::.:... |||.
Mouse   329 QAAPDQLVLYFVMDLLKDMPGLPGLFVACLFSGSLSTISSAFNSLATVTMEDLIQPWFPQ-LTET 392

  Fly   397 QTAFVMRSVVVVFGIIFVALVFAVEKLGAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALL 461
            :...:.|.:...:|::.:.:.:....||:|||..:::..:..|||||:|..|:..|..|..||::
Mouse   393 RAIMLSRGLAFAYGLVCLGMAYISSHLGSVLQAALSIFGMVGGPLLGLFCLGLFFPCANPLGAIV 457

  Fly   462 GGFSSLIVMAWMCVSAQRDLVTGDLVYKRK----------PYSTMGCNYTFAGEPREFASLALDG 516
            |..:.|.:..|:.:        |.:|.:..          ..|.:..|.|.|         |:..
Mouse   458 GLLTGLTMAFWIGI--------GSIVSRMSSAVAPPPLNGSSSFLPANVTVA---------AVTT 505

  Fly   517 AISSVPSAPFQL---YRISYLYFTLFGALVTIVVALVTSLLLRETDLDGVDTRLLTP 570
            .:.|..|.|..|   |.:|||:::...:...|||.|:.|||     ..|:..|.|.|
Mouse   506 VMPSTLSKPTGLQHFYSLSYLWYSAHNSTTVIVVGLIVSLL-----TGGMRGRSLNP 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	177/552 (32%)
Slc5a6	NP_001171092.1	SLC5-6-like_sbd	23..548	CDD:320982	180/562 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820