DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and Slc5a5

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_443215.2	Gene:	Slc5a5 / 114613	RGDID:	69267	Length:	618	Species:	Rattus norvegicus

Alignment Length:	599	Identity:	201/599 - (33%)
Similarity:	314/599 - (52%)	Gaps:	41/599 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 SFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQMKIFPITMS 76
            :||..||.||..||.:...||::..|          |.|.:.   ||..:..||||:...|:.:|
  Rat    11 TFGAWDYGVFATMLLVSTGIGLWVGL----------ARGGQR---SADDFFTGGRQLAAVPVGLS 62

  Fly    77 LISSFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRYNR 141
            |.:||:|.:.:||.|.|...||.:::::....:|......:.|||:|:.|.|.|||:|||.|::|
  Rat    63 LAASFMSAVQVLGVPAEAARYGLKFLWMCAGQLLNSLLTAFLFLPIFYRLGLTSTYQYLELRFSR 127

  Fly   142 SLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDV 206
            ::||.|::.::||::|:..||||.||:..||.||::|........::|..||.:||:||||||||
  Rat   128 AVRLCGTLQYLVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTLYTTVGGMKAVVWTDV 192

  Fly   207 IQTLIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVLGGVAHWLK 271
            .|.::|.....::|.:|.:.:|||..:...||..:|:.:.:|..|...||||::.::||...||.
  Rat   193 FQVVVMLVGFWVILARGVILLGGPRNMLSLAQNHSRINLMDFDPDPRSRYTFWTFIVGGTLVWLS 257

  Fly   272 SNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLETKLAQRND 336
            ...::|..:|||::..|...|::|:.....|:...:......|::::..|..||||.|......|
  Rat   258 MYGVNQAQVQRYVACHTEGKAKLALLVNQLGLFLIVASAACCGIVMFVYYKDCDPLLTGRISAPD 322

  Fly   337 QLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFV 401
            |.:||||:|.....||:||:|:|..:|..||:.||.:|:::||.:||.:|. |...|...:..|:
  Rat   323 QYMPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKP-RMPGLAPRKLVFI 386

  Fly   402 MRSVVVVFGIIFVALVFAVEKL--GAVLQLTITLSSVANGPLLGIFTAGVMLPWVNSKGALLGGF 464
            .:.:..::|...:. |.|:..|  |.|||.:.|:..|.:|||||.||.|::||..|:.|.|.|..
  Rat   387 SKGLSFIYGSACLT-VAALSSLLGGGVLQGSFTVMGVISGPLLGAFTLGMLLPACNTPGVLSGLA 450

  Fly   465 SSLIVMAWMCVSAQRDLVTGDLVYKRKPYSTMGC--NYTFAGEPREFASLALDGAISS-----VP 522
            :.|.|..|:.|.|.. ...|:......|.|..||  :....|.|.  |:.|.:|..||     .|
  Rat   451 AGLAVSLWVAVGATL-YPPGEQTMGVLPTSAAGCTNDSVLLGPPG--ATNASNGIPSSGMDTGRP 512

  Fly   523 SAPFQLYRISYLYFTLFGALVTIVVALVTSLLLRETDLDGVDTRLLTPFVRRWLERRRHRRSKIP 587
            :.....|.|||||:...|.|.|::...:.|.|...|....:...||      |.:..|...|..|
  Rat   513 ALADTFYAISYLYYGALGTLTTMLCGALISYLTGPTKRSSLGPGLL------WWDLARQTASVAP 571

  Fly   588 DSGQKSSNKQETKT 601
                    |::|.|
  Rat   572 --------KEDTAT 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	188/546 (34%)
Slc5a5	NP_443215.2	SLC5sbd_NIS	15..549	CDD:271393	189/551 (34%)
Slc5a5	NP_443215.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	587..618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340261
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.850