Protein Alignment rumpel and Slc5a10

DIOPT Version :10

• Sequence 1: NP_572397.1
• Gene: rumpel / 31674
• FlyBaseID: FBgn0029950
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: XP_006532041.1
• Gene: Slc5a10 / 109342
• MGIID: 1926089
• Length: 611
• Species: Mus musculus
• Alignment Length: 577
• Identity: 142/577 - (24%)
• Similarity: 236/577 - (40%)
• Gaps: 137/577 - (23%)

  Fly    30 VIGIYFCLQLRL----ESRKQKANGSEEAASSAASYLVGGRQMKIFPITMSLI-SSFISG--ITL 87
            ||.:||.|.:.:    ..|..|        ::.:.|.:.||.|..:||..||. ||..||  :.|
Mouse    58 VISVYFALNVAVGIWSACRANK--------NTVSGYFLAGRDMAWWPIGASLFASSEGSGLFVGL 114

  Fly    88 LGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYKYLEQRY-NRSLRLFGSVMF 151
            .|:       ||     .|.|.:.||           |.|:::..:|:::|: .:.:|.:.||:.
Mouse   115 AGS-------GA-----AGGLAVAGF-----------EWNIVTLPEYIQKRFGGQRIRTYLSVLS 156

  Fly   152 IVASLLW-LPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQTLIMFGA 215
            ::.|:.. :.|.:|..|:..:...|.|.::.|.:...:...||..|||..|::||.:||:||...
Mouse   157 LMLSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTIIMVVG 221

  Fly   216 MALVLIKGTLDIGGPGVVWQK-----AQETARLEVPN-----------------FSADLSERYTF 258
            ..::.:|....|||    :::     ||......:||                 .:.||......
Mouse   222 AVILAVKAFNQIGG----YEQLEAAYAQAIPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWTGMT 282

  Fly   259 YSLVLGGVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIY----- 318
            :.|.:....:|    ...|.::||.||...|..|:..  :.:|..|..|.:    ||:|.
Mouse   283 FGLTIMATWYW----CTDQVIVQRSLSARNLNHAKAG--SILASYLKMLPM----GLMIMPGMIS 337

  Fly   319 ----------ATYSQCDPLETKLAQ--RNDQLLPLLVMDTLGSYP-GLPGVFVAGVFSAALSSLS 370
                      ...|:|  |....|:  .::...|.|||:.:   | ||.|:.:|.:.:|.||||:
Mouse   338 RVLFPDDVGCVVPSEC--LRACGAEIGCSNIAYPKLVMELM---PIGLRGLMIAVMMAALLSSLT 397

  Fly   371 TGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVMRSVVVVFGIIFVALVFAVEKLGAVLQLTITLSS 435
            :..||.|.:...|..:..|.| ..|.:...|.|.|:||...:.||.:..::...:. ||.|.:.|
Mouse   398 SIFNSSSTLFTMDIWRQLRPS-AGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSG-QLFIYMQS 460

  Fly   436 VANG---PLLGIFTAGVMLPWVNSKGALLGGFSSLIVMAWMCVSAQRDLVTGDLVYKRKPYSTMG 497
            |.:.   |:..||..|:.....|.:||..|      :||.:.|.|.|.::  :.:|...|
Mouse   461 VTSSLAPPVTAIFILGIFWRRANEQGAFWG------LMAGLVVGALRLVL--EFLYPEPP----- 512

  Fly   498 CNYTFAGEPREFASLALDGAISSVPSAPFQLYRISYLYFTLFGALVTIVVALVTSLL 554
            |                    ..:.:.|..|..:.||:|.:...|:|..|....|||
Mouse   513 C--------------------GQIDTRPAPLRSLHYLHFAIALFLLTCAVMAAGSLL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rumpel	NP_572397.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	140/575 (24%)
Slc5a10	XP_006532041.1	SLC5-6-like_sbd	52..611	CDD:444915	142/577 (25%)