DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and slc5a5

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001116937.1	Gene:	slc5a5 / 100144711	XenbaseID:	XB-GENE-486472	Length:	600	Species:	Xenopus tropicalis

Alignment Length:	587	Identity:	180/587 - (30%)
Similarity:	300/587 - (51%)	Gaps:	54/587 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EELRASLQSFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQM 68
            |.|..||    | ||.||..||.:...||:::..          ::|.::.:.   .:..|||.|
Frog    49 ESLTFSL----W-DYGVFATMLIMSTGIGLFYAF----------SHGGQKTSD---DFFTGGRSM 95

  Fly    69 KIFPITMSLISSFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYK 133
            ...|:.:||.:||:|.:.:||.|.|.|.||.:::.:....:|......|.|:|:|:.|.:.|||:
Frog    96 SAVPVGLSLSASFMSAVQVLGVPAEAYRYGVKFLQMCIGQILNSVMTAYIFMPIFYRLGITSTYQ 160

  Fly   134 YLEQRYNRSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGL 198
            |||.|::||:||:|::.|::.::.:..||||.||:..||.||::|.........:|.|||.:||:
Frog   161 YLEMRFSRSVRLYGTIQFLLGTMFYTGIVIYAPALILNQVTGLDIWASLFSTGAICTFYTTVGGM 225

  Fly   199 KAVVWTDVIQTLIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVL 263
            |||:||||.|..:|......|.|:|...:||.....:.|...:|:...:|..|...||||::.|:
Frog   226 KAVIWTDVFQVFVMLSGFFAVAIRGIHLVGGFSDAIEVAGNYSRINFGDFDPDPRRRYTFWTFVM 290

  Fly   264 GGVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLE 328
            |....||....::|..:|||::..|..:|::||......:...:......|::::..|..||||.
Frog   291 GSTFLWLSMYGVNQAQVQRYVACKTENEAKLAILVNQVALCVIVSSAVTCGIVMFVYYLNCDPLL 355

  Fly   329 TKLAQRNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSP- 392
            .......||.:|..|::....|||:||:|:|..:|..||:.||.:|:::||.:||.::.  |.|
Frog   356 AGYVSAPDQYMPYFVLEIFDQYPGIPGLFLACAYSGTLSTASTSINAMAAVTVEDLIRP--KYPN 418

  Fly   393 LTEGQTAFVMRSVVVVFGIIFVALVFAVEKL--GAVLQLTITLSSVANGPLLGIFTAGVMLPWVN 455
            ::..:...:.:.:.:.:|...:. |.|:..|  |.|||.:.|:..|.:|||||.|..|:.....|
Frog   419 ISTKKLTLISKGLSLAYGCSCIT-VAALSSLLGGGVLQGSFTVMGVISGPLLGAFMLGMFFASCN 482

  Fly   456 SKGALLGGFSSLIVMAWMCVSAQRDLVTGDLVYKRKPYST--MGCNYTFAGE-PREFASLAL--- 514
            :.|...|....|::..|:.|        |..:|   |.|.  ||...|||.. |...:|..:
Frog   483 TIGVFAGLLVGLVISLWVAV--------GGTIY---PPSAEMMGVLPTFAEHCPLYNSSKGIIYG 536

  Fly   515 DGAISSV------PSAPFQLYRISYLYFTLFGALVTIVVALVTSLLL----RETDLDGVDTRLLT 569
            ...:.::      |:....||.:||||:.:.|.:.|:::.::.|...    |||...|:   ::.
Frog   537 PAPVQNITHTLERPALADDLYALSYLYYGVVGTISTVIIGVIVSKFTGPTKRETIAPGL---MVG 598

  Fly   570 PF 571
            ||
Frog   599 PF 600

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	169/552 (31%)
slc5a5	NP_001116937.1	SLC5sbd_NIS	56..587	CDD:271393	170/558 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1180002at2759
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42985
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020