Protein Alignment rumpel and slc5a5

DIOPT Version :10

• Sequence 1: NP_572397.1
• Gene: rumpel / 31674
• FlyBaseID: FBgn0029950
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001116937.1
• Gene: slc5a5 / 100144711
• XenbaseID: XB-GENE-486472
• Length: 600
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 180/587 - (30%)
• Similarity: 300/587 - (51%)
• Gaps: 54/587 - (9%)

  Fly     4 EELRASLQSFGWPDYLVFCLMLAICAVIGIYFCLQLRLESRKQKANGSEEAASSAASYLVGGRQM 68
            |.|..||    | ||.||..||.:...||:::..          ::|.::.:.   .:..|||.|
 Frog    49 ESLTFSL----W-DYGVFATMLIMSTGIGLFYAF----------SHGGQKTSD---DFFTGGRSM 95

  Fly    69 KIFPITMSLISSFISGITLLGTPTEVYLYGAQYMYIMGSLVLMGFCMYYFFLPVFHELNLISTYK 133
            ...|:.:||.:||:|.:.:||.|.|.|.||.:::.:....:|......|.|:|:|:.|.:.|||:
 Frog    96 SAVPVGLSLSASFMSAVQVLGVPAEAYRYGVKFLQMCIGQILNSVMTAYIFMPIFYRLGITSTYQ 160

  Fly   134 YLEQRYNRSLRLFGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGL 198
            |||.|::||:||:|::.|::.::.:..||||.||:..||.||::|.........:|.|||.:||:
 Frog   161 YLEMRFSRSVRLYGTIQFLLGTMFYTGIVIYAPALILNQVTGLDIWASLFSTGAICTFYTTVGGM 225

  Fly   199 KAVVWTDVIQTLIMFGAMALVLIKGTLDIGGPGVVWQKAQETARLEVPNFSADLSERYTFYSLVL 263
            |||:||||.|..:|......|.|:|...:||.....:.|...:|:...:|..|...||||::.|:
 Frog   226 KAVIWTDVFQVFVMLSGFFAVAIRGIHLVGGFSDAIEVAGNYSRINFGDFDPDPRRRYTFWTFVM 290

  Fly   264 GGVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFLMICGYTGLLIYATYSQCDPLE 328
            |....||....::|..:|||::..|..:|::||......:...:......|::::..|..||||.
 Frog   291 GSTFLWLSMYGVNQAQVQRYVACKTENEAKLAILVNQVALCVIVSSAVTCGIVMFVYYLNCDPLL 355

  Fly   329 TKLAQRNDQLLPLLVMDTLGSYPGLPGVFVAGVFSAALSSLSTGLNSLSAVVLEDFVKTFRKSP- 392
            .......||.:|..|::....|||:||:|:|..:|..||:.||.:|:::||.:||.::.  |.|
 Frog   356 AGYVSAPDQYMPYFVLEIFDQYPGIPGLFLACAYSGTLSTASTSINAMAAVTVEDLIRP--KYPN 418

  Fly   393 LTEGQTAFVMRSVVVVFGIIFVALVFAVEKL--GAVLQLTITLSSVANGPLLGIFTAGVMLPWVN 455
            ::..:...:.:.:.:.:|...:. |.|:..|  |.|||.:.|:..|.:|||||.|..|:.....|
 Frog   419 ISTKKLTLISKGLSLAYGCSCIT-VAALSSLLGGGVLQGSFTVMGVISGPLLGAFMLGMFFASCN 482

  Fly   456 SKGALLGGFSSLIVMAWMCVSAQRDLVTGDLVYKRKPYST--MGCNYTFAGE-PREFASLAL--- 514
            :.|...|....|::..|:.|        |..:|   |.|.  ||...|||.. |...:|..:
 Frog   483 TIGVFAGLLVGLVISLWVAV--------GGTIY---PPSAEMMGVLPTFAEHCPLYNSSKGIIYG 536

  Fly   515 DGAISSV------PSAPFQLYRISYLYFTLFGALVTIVVALVTSLLL----RETDLDGVDTRLLT 569
            ...:.::      |:....||.:||||:.:.|.:.|:::.::.|...    |||...|:   ::.
 Frog   537 PAPVQNITHTLERPALADDLYALSYLYYGVVGTISTVIIGVIVSKFTGPTKRETIAPGL---MVG 598

  Fly   570 PF 571
            ||
 Frog   599 PF 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rumpel	NP_572397.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	169/552 (31%)
slc5a5	NP_001116937.1	SLC5sbd_NIS	56..587	CDD:271393	170/558 (30%)