DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9657 and slc5a3a

DIOPT Version :9

Sequence 1:	NP_001284983.1	Gene:	CG9657 / 31674	FlyBaseID:	FBgn0029950	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001153309.1	Gene:	slc5a3a / 100004287	ZFINID:	ZDB-GENE-090312-3	Length:	671	Species:	Danio rerio

Alignment Length:	606	Identity:	148/606 - (24%)
Similarity:	242/606 - (39%)	Gaps:	134/606 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 VIGIYFCLQLRLESRKQ-KANGSEEAASSAASYLVGGRQMKIFPITMSLISSFISG---ITLLGT 90
            |:.:||.|.|....... :||     ..:.:.|.:.||.|..|.|..||..|.|..   |.|.|:
Zfish    12 VVAMYFVLVLCFGFFSMWRAN-----RGTVSGYFLAGRSMNWFVIGASLFVSNIGSEHFIGLAGS 71

  Fly    91 PTEVYLYGAQYMYIMGS--------LVLMGFCMYYFFLPVFHELNLISTYKYLEQRY--NRSLRL 145
                   ||.....:|:        |.|:|    :.|:||:....:.:..:||.:|:  ||....
Zfish    72 -------GAASGLAVGAWEFNAILLLQLLG----WVFIPVYIHSGVYTMPEYLSKRFGGNRLKIY 125

  Fly   146 FGSVMFIVASLLWLPIVIYVPAIAFNQATGVNIHIVTPIVCVVCIFYTCIGGLKAVVWTDVIQTL 210
            |.|:..::.....|.:.:|..|:...::.|.|:::...::..:....|..|||.||::||.:|..
Zfish   126 FASLTLLLYIFTKLSVDLYSGALFIQESLGWNLYLSIILLITLTALLTVTGGLVAVIYTDTLQAF 190

  Fly   211 IMF-GAMALVLIKGTLDIGG------------PGVVW----------------QKAQETARLEVP 246
            :|. ||:.|:.| ..:.:||            |.:.:                .||.....|..|
Zfish   191 LMISGALCLMAI-SLVKVGGLEGLRTKYMNALPNITFITLENNLTYSNSCHVNPKADSFKLLRSP 254

  Fly   247 NFSADLSERYTFYSLVLG----GVAHWLKSNAISQNMIQRYLSLPTLRDARIAIWTFIAGVLAFL 307
                 |.:...:.:.:||    .:.:|    ...|.::||.|:...:..|:.:  |.:||||..|
Zfish   255 -----LDKDLPWPAFLLGQTPASIWYW----CADQVIVQRVLAARNIAHAKGS--TLLAGVLKVL 308

  Fly   308 -----MICGYTGLLIYATYSQCDPLETKLAQRNDQ------LLPLLVMDTLGSYP-GLPGVFVAG 360
                 :|.|....:::|....|...|..:...|.:      ..|.|||:.:   | ||.|:.:|.
Zfish   309 PMFIIVIPGMISRVLFADELACIGPEHCMQVCNSRAGCTNTAYPRLVMNIM---PVGLRGLMMAV 370

  Fly   361 VFSAALSSLSTGLNSLSAVVLEDFVKTFRKSPLTEGQTAFVMRSVVVVFGIIFVALV-FAVEKLG 424
            :.:|.:|.|.:..||.|.:...|..|..|....:: :...|.|..||:...|.:|.| |.:|..|
Zfish   371 MLAALMSDLDSIFNSASTIFTLDIYKMIRHQASSK-ELMVVGRLFVVLIVAISIAWVPFVIEMQG 434

  Fly   425 AVLQLTI-TLSSVANGPLLGIFTAGVMLPWVNSKGALLGGFSSLIVMAWMCVSAQRDLVTGDLVY 488
            ..:.|.| .:|.....|:..:|..||:....|..||..|||..||:.....:.|        .||
Zfish   435 GQMFLYIQEVSDYLTPPIAALFLLGVLWKRCNETGAFWGGFVGLILGIVRLILA--------FVY 491

  Fly   489 KRKPYSTMGCNYTFAGEPREFASLALDGAISSVPSAPFQLYRISYLYF--TLF--GALVTIVVAL 549
             |:|    .|:                    ||...|..:..:.::|.  .||  ...|.:||:|
Zfish   492 -REP----DCD--------------------SVDDRPAFIKDVHFMYVAAVLFWVSGFVMVVVSL 531

  Fly   550 VTSLLLRE----TDLDGVDTR 566
            .|:...:|    |.|.|:..|
Zfish   532 CTNPPSKEQISKTTLWGLRNR 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9657	NP_001284983.1	SLC5sbd_NIS-SMVT	16..554	CDD:271383	143/588 (24%)
slc5a3a	NP_001153309.1	SLC5-6-like_sbd	9..671	CDD:294310	148/606 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580122
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740