DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18155 and AAE13

DIOPT Version :9

Sequence 1:	NP_996360.2	Gene:	CG18155 / 31668	FlyBaseID:	FBgn0029945	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_001319565.1	Gene:	AAE13 / 820862	AraportID:	AT3G16170	Length:	608	Species:	Arabidopsis thaliana

Alignment Length:	609	Identity:	155/609 - (25%)
Similarity:	236/609 - (38%)	Gaps:	125/609 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 HSFDEEERS--NVVVPTFKKAMLYPDEIAVKDINGEYTYFQLYMAAKRL------------GIQI 85
            |.|..:..|  .|....|.:|....|.||:|.....|:|.||..:|.|:            |.:.
plant    55 HLFSSQSGSLMEVFKAAFSEASNSCDRIAIKADGKSYSYGQLTSSALRISKLFLKDDTTNGGQET 119

  Fly    86 SNICGGAAL--SNVTYLCSNNALWIAIQWSCWISGQVAVPLESGQAIDQLQRQASNCKTKLLIAT 148
            ....|..:|  :.:..:...:|.::|.....|.||.|||||.......:|....::....||::|
plant   120 KKYEGFGSLKGARIGIVAKPSAEFVAGVLGTWFSGGVAVPLALSYPEAELLHVMNDSDISLLLST 184

  Fly   149 KEFESLAQELSQGVKSATIILDHSFLPTAESVSSTSMYAKQLVAIQGVIVTENTFPNDFYSKA-- 211
            ::.....:.::  .||....  |...|...|.|.|              |..|.|.:|.:...
plant   185 EDHSETMKTIA--AKSGARF--HLIPPVVNSTSET--------------VACNQFQDDSFEAEGK 231

  Fly   212 ----PAMLIYTPNAVNSPKPVLLTHRNIEAQMRCLIGTWHLGPTDCMLPILSMNRMHA---ALAA 269
                ||:::||......||.|:.||.:|.:|:|.|...|.....|..|..|.::.:|.   ||.|
plant   232 FLDDPALIVYTSGTTGKPKGVVHTHNSINSQVRMLTEAWEYTSADHFLHCLPLHHVHGLFNALFA 296

  Fly   270 VLSVGGNVVLQQKFDGH---NAWSALLGIN-SPSKQRVTLFLAMPIVYKRLIVEYEKMFAKDSRM 330
            .|.....|....||...   ..|.....:| ..:...:|:|..:|.:|.|||..||.|   |..|
plant   297 PLYARSLVEFLPKFSVSGIWRRWRESYPVNDEKTNDSITVFTGVPTMYTRLIQGYEAM---DKEM 358

  Fly   331 VEYIVNHCRQKIRLMATAFALLPDSVFYRWREITGQNIYEYYGMMETGLVLGHPLNKRQRDSPHN 395
            .:......| |:|||.:..:.||..|.::|..|||..:.|.|||.|..:.:.:||..
plant   359 QDSSAFAAR-KLRLMMSGSSALPRPVMHQWESITGHRLLERYGMTEFVMAMSNPLRG-------- 414

  Fly   396 GPTAVAMANNTAPNDYRPGTLGSPLKGVTARLISNKGDELITCKNELGGSVDSGLIPVEDIGGDA 460
                   |.|.       ||:|.||.||.|::   |.||     |:..|
plant   415 -------ARNA-------GTVGKPLPGVEAKI---KEDE-----NDANG---------------- 441

  Fly   461 SLAGTIIGELQIAGSNLVSNTLANNNQEMEHKGTTNNEEQENNQDGFFKTGDICAYRNGNFYFL- 524
                  :||:.:...:|..          |:.......::...:||:|||||........:|.:
plant   442 ------VGEICVKSPSLFK----------EYWNLPEVTKESFTEDGYFKTGDAGRVDEDGYYVIL 490

  Fly   525 -SKSSDIFTVGGYKVYGSEIKKVLISHPNINDVAVLGIPNKMWGHRLGVICIVSPDAD------- 581
             ..|:||..|||||:...||:..|:.||.:.:..|||:.:..:|..:..|.|....|.
plant   491 GRNSADIMKVGGYKLSALEIESTLLEHPTVAECCVLGLTDNDYGEAVTAIIIAESAAKKRREDES 555

  Fly   582 ---IDLDAIKTYCYRHLPAHKCPT 602
               |.|:.:..:....|..:|.||
plant   556 KPVITLEELCGWAKDKLAPYKLPT 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	150/589 (25%)
CG18155	NP_996360.2	AFD_class_I	58..607	CDD:302604	149/584 (26%)
AAE13	NP_001319565.1	MCS	80..597	CDD:213307	149/584 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	109	1.000	Domainoid score	I2139
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	143	1.000	Inparanoid score	I1772
OMA	1	1.010	-	-		QHG55233
OrthoDB	1	1.010	-	-		D533939at2759
OrthoFinder	1	1.000	-	-		FOG0002270
OrthoInspector	1	1.000	-	-		oto3056
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2297
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.840