DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18155 and Acsf2

DIOPT Version :9

Sequence 1:	NP_996360.2	Gene:	CG18155 / 31668	FlyBaseID:	FBgn0029945	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_001030123.1	Gene:	Acsf2 / 619561	RGDID:	1562656	Length:	615	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	103/536 - (19%)
Similarity:	183/536 - (34%)	Gaps:	122/536 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 NNALWIAIQWSCWISGQVAVPLESGQAIDQLQRQASNCKTKLLIATKEFES------LAQELSQG 161
            |:..|:.||.:...:|.:.|.:.......:|:........|.::..|:|::      |.|...:.
  Rat   133 NSYAWVLIQLATAQAGIILVSVNPAYQASELEYVLRKVGCKGIVFPKQFKTQQYYNILKQVCPEL 197

  Fly   162 VKSATIILDHSFLPTAESVSST------SMYAKQLVAIQGVIVTENTFPNDFYSKA------PAM 214
            .|:....|....||...:|.|.      ::...::||..|   .|.......|.:.      |..
  Rat   198 EKAQPGALKSERLPDLTTVISVDAPLPGTLLLDEVVAAGG---KEQNLAQLRYHQGFLSCYDPIN 259

  Fly   215 LIYTPNAVNSPKPVLLTHRNIEAQMRCLIGTWHLGPTDCMLPILSMNRMHAALAAVL-----SVG 274
            :.:|.....:||...|:|.||..... |||      ....:|..:...:...|...|     |||
  Rat   260 IQFTSGTTGNPKGATLSHHNIVNNSN-LIG------QRLKMPAKTAEELRMVLPCPLYHCLGSVG 317

  Fly   275 GNVV----------LQQKFDGHNAWSALLGINSPSKQRVTLFLAMPIVYKRLIVEYEKMFAKDSR 329
            |.:|          ....|:|..|..|:      |:::.||....|.::..::.:      .|..
  Rat   318 GTMVSVVHGATLLLSSPSFNGKKALEAI------SREKGTLLYGTPTMFVDILNQ------PDFS 370

  Fly   330 MVEYIVNHCRQKIRLMATAFALLPDSVFYRWREITGQNIYEYYGMMETGLVLGHPLNKRQRDSPH 394
            ..::..      ||....|.:|.|..:.        :.|.....|.|..:|.|         :..
  Rat   371 SYDFTT------IRGGVIAGSLAPPELI--------RAIISKMNMKELVVVYG---------TTE 412

  Fly   395 NGPTAVAMANNTAPND---YRPGTLGSPLKGVTARLISNKGDELITCKNELGGSVDSGLIPVEDI 456
            |.|  |...|  .|.|   .:.|::|..:....|::::.:..||....           :|
  Rat   413 NSP--VTFMN--FPEDTLEQKAGSVGRIMPHTEAQIVNMETGELTKLN-----------MP---- 458

  Fly   457 GGDASLAGTIIGELQIAGSNLVSNTLANNNQEMEHKGTTNNEEQENNQDGFFKTGDICAYRNGNF 521
                       |||.|.|..::........:..|..|          ||.:::||||.:.....|
  Rat   459 -----------GELCIRGYCVMQGYWGEPQKTFETVG----------QDRWYRTGDIASMDEQGF 502

  Fly   522 -YFLSKSSDIFTVGGYKVYGSEIKKVLISHPNINDVAVLGIPNKMWGHRLGVICIVSPDADIDLD 585
             ..:.:|.|:...||..:|.:|::.....||.:.:..|:|:.:...|..:.....:........:
  Rat   503 CRIVGRSKDMIIRGGENIYPAELEDFFHKHPQVQEAQVVGVKDDRMGEEICACIRLKSGETTTEE 567

  Fly   586 AIKTYCYRHLPAHKCP 601
            .||.:|...:...|.|
  Rat   568 EIKAFCKGKISHFKIP 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	103/536 (19%)
CG18155	NP_996360.2	AFD_class_I	58..607	CDD:302604	103/536 (19%)
Acsf2	NP_001030123.1	PRK08315	57..615	CDD:236236	103/536 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810