DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18155 and pdgy

DIOPT Version :9

Sequence 1:	NP_996360.2	Gene:	CG18155 / 31668	FlyBaseID:	FBgn0029945	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	580	Identity:	120/580 - (20%)
Similarity:	213/580 - (36%)	Gaps:	163/580 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 EYTYFQLYMAAKRLGIQIS---NICGGAALSNVTYLCSNN------ALWIAIQWSCWISGQVAVP 123
            :||:.|:..|:....:::.   |:    ...:|..:|..|      |...||:     :|.....
  Fly   102 QYTFAQMRDASAAFAVRLQTKFNL----QKPDVLAICLPNLPEYPIATLGAIE-----AGLTVTT 157

  Fly   124 LESGQAIDQLQRQASNCKTKLLIAT-KEFESLAQELSQGVKSATIILDHSFLPTA-------ESV 180
            :......|::.||.:....|.|:.| ..|.:|:|        |:.::... :|.|       |::
  Fly   158 VNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQ--------ASKLVGRQ-IPIAVVRTSAEEAL 213

  Fly   181 SSTSMYAKQLVAIQGVIVTENTFPNDFYSKAPAMLIYTPNAVNSPKPVLLTHRNIEA---QMRCL 242
            ...::...:|.:.|.|...:...|.:..:.....|.::......||.|:|:|.||.:   |::..
  Fly   214 PEGAIDFSELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQAS 278

  Fly   243 IGTWHLGPTDCMLPILSMNRMHAALAAVLSVGGNVVLQQKFDGHNAWSALLGINSPSKQRVTLFL 307
            :      |.|.|.|   .|.:...|......|..||:..|          ||
  Fly   279 L------PLDLMGP---QNTLPGVLPFFHIYGLTVVMLSK----------LG------------- 311

  Fly   308 AMPIVYKRLIVEYEKMFAKDSRMVEYIVNHCRQKIRLMATAFALLPDSVFYRWREITGQNIYEYY 372
                                        ..||     :||.....||. |.|       ::.:|.
  Fly   312 ----------------------------QGCR-----LATMPCFKPDD-FMR-------SLDKYQ 335

  Fly   373 GMMETGLV-------LGHPLNKRQRDSPH-----NGPTAVAMAN-----NTAPND-YRPG---TL 416
            |.: ..||       :.|| ...|..:||     :|...:...:     |..||. ::.|   |.
  Fly   336 GSI-LNLVPPIALFMINHP-KLTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTE 398

  Fly   417 GSPLKGVTARLISNKGDELITCKNELGGSVDSGLIPVEDIGGDASLAG-TIIGELQIAGSNLVSN 480
            .||:.     |::.:|:::......|..|.::.::|::  |.||...| ...|||.:.|..:::
  Fly   399 ASPVV-----LLTPEGNKVYASTGVLPASTEAKIVPLD--GSDAKGVGPRTTGELCVRGPQVMA- 455

  Fly   481 TLANNNQEMEHKGTTNNEEQENNQDGFF-----KTGDICAY-RNGNFYFLSKSSDIFTVGGYKVY 539
                        |..||:|.  ||..|:     ::||:..| .:|.||...:..::..|.|::|.
  Fly   456 ------------GYLNNDEA--NQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVP 506

  Fly   540 GSEIKKVLISHPNINDVAVLGIPNKMWGHRLGVICIVSPDADIDLDAIKTYCYRHLPAHK 599
            .:|::.||..||.|.:.||.|||::..|.....|.::........:.|..|....:..:|
  Fly   507 PAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYK 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	120/580 (21%)
CG18155	NP_996360.2	AFD_class_I	58..607	CDD:302604	120/580 (21%)
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	120/580 (21%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	120/580 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R434
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940