Protein Alignment CG18155 and DIP2A

DIOPT Version :9

• Sequence 1: NP_996360.2
• Gene: CG18155 / 31668
• FlyBaseID: FBgn0029945
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: XP_011527794.1
• Gene: DIP2A / 23181
• HGNCID: 17217
• Length: 1607
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 112/611 - (18%)
• Similarity: 195/611 - (31%)
• Gaps: 226/611 - (36%)

  Fly   102 SNNALWIAIQWSCWISGQVAVPLESGQAIDQLQRQASNCKTKLLIAT-KEFESLAQELSQ-GVKS 164
            |:..:::...:.|.::..|.||:|    :...::.|.:.:...|:.: ..|.:|..:..| |:..
Human   442 SDPVMFMVAFYGCLLAELVPVPIE----VPLTRKDAGSQQVGFLLGSCGVFLALTTDACQKGLPK 502

  Fly   165 ATIILDHSFLPTAESVSSTSMYAKQLVAIQGVIVTENTFPNDFYSKA------PAMLIYTPNAVN 223
            |         .|.|..:.........:.|.|..:.:.  |.|::..|      .|.:.|..:...
Human   503 A---------QTGEVAAFKGWPPLSWLVIDGKHLAKP--PKDWHPLAQDTGTGTAYIEYKTSKEG 556

  Fly   224 SPKPVLLTHRNIEAQMRCL---------------------IGTWHLGPTDCMLPILS--MNRMHA 265
            |...|.::|.::.||.|.|                     .|.||        .:|:  |||||
Human   557 STVGVTVSHASLLAQCRALTQACGYSEAETLTNVLDFKRDAGLWH--------GVLTSVMNRMH- 612

  Fly   266 ALAAVLSVGGNVVLQQKFDGHNAWSALLGINSPS-KQRVTLFLAMPIVYKRLIVEYEKMFAKDSR 329
                |:||.               .||:..|..| .|:|..:.|...:.|...:.:..:..:..|
Human   613 ----VVSVP---------------YALMKANPLSWIQKVCFYKARAALVKSRDMHWSLLAQRGQR 658

  Fly   330 MVEYIVNHCRQKIRLMATAFALLPDSV-----FYRWREITGQNIYEYYGMMETGLVLGHPLNKRQ 389
            .|..      ..:|::..|....|.|:     |.        |:::..|:
Human   659 DVSL------SSLRMLIVADGANPWSISSCDAFL--------NVFQSRGL--------------- 694

  Fly   390 RDSPH------NGPTAVAMANNTAPNDYRPGTLGSP--------LKGVTARLISNKGDELITCKN 440
              .|.      :.|.|:.:|..      ||..||.|        :.|::..:|....:|.::
Human   695 --RPEVICPCASSPEALTVAIR------RPPDLGGPPPRKAVLSMNGLSYGVIRVDTEEKLS--- 748

  Fly   441 ELGGSVDSGLIPVEDIG--------------GDASLAGT-IIGELQIAGSNLVSNTLANNNQEME 490
                     ::.|:|:|              |...|..| .:||:.::.|       |.......
Human   749 ---------VLTVQDVGQVMPGANVCVVKLEGTPYLCKTDEVGEICVSSS-------ATGTAYYG 797

  Fly   491 HKGTTNNEEQENNQDGFFK-----TGDICAY-----RNGNFYFLSKSSDIFTVG---GYKVYGSE 542
            ..|.|.|         .|:     ||....:     |.|...|:...:.:|.||   |..|.|
Human   798 LLGITKN---------VFEAVPVTTGGAPIFDRPFTRTGLLGFIGPDNLVFIVGKLDGLMVTG-- 851

  Fly   543 IKKVLISHPNINDVAVLGI---PNK-MWGHRLGVICIV-------------SPDAD--------- 581
                 :...|.:||....:   |.| ::..|:.|..:.             .|||.
Human   852 -----VRRHNADDVVATALAVEPMKFVYRGRIAVFSVTVLHDDRIVLVAEQRPDASEEDSFQWMS 911

  Fly   582 -----ID-LDAIKTYCYRHLPAHKCP 601
                 || :..:..||...:||:..|
Human   912 RVLQAIDSIHQVGVYCLALVPANTLP 937

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	112/611 (18%)
		AFD_class_I	58..607	CDD:302604	112/611 (18%)
DIP2A	XP_011527794.1	DMAP_binding	9..158	CDD:283995
		CaiC	360..959	CDD:223395	112/611 (18%)
		AFD_class_I	392..956	CDD:302604	112/611 (18%)
		AMP-binding	1027..1501	CDD:278902
		AFD_class_I	1044..1596	CDD:302604

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900