Protein Alignment CG18155 and acs-1

DIOPT Version :9

• Sequence 1: NP_996360.2
• Gene: CG18155 / 31668
• FlyBaseID: FBgn0029945
• Length: 610
• Species: Drosophila melanogaster
• Sequence 2: NP_001023937.1
• Gene: acs-1 / 179043
• WormBaseID: WBGene00018488
• Length: 623
• Species: Caenorhabditis elegans
• Alignment Length: 649
• Identity: 117/649 - (18%)
• Similarity: 217/649 - (33%)
• Gaps: 207/649 - (31%)

  Fly    31 EKLRHSFDEEERSNVVVPTFKKAMLYPDEIAVKDINGEYTYFQLYMAAKRLGIQISNICGGAAL- 94
            ::||.:.|:       ||. |:.:::..|...|      ||.|:...|:.|.      ||...|
 Worm    70 DRLRSAVDQ-------VPD-KEFLIFKREGIRK------TYSQVATDAENLA------CGLLHLG 114

  Fly    95 ----SNVTYLCSNNALWIAIQWSCWISGQVAVPLESGQAIDQLQRQASNCKTKLLIATKEFESLA 155
                ..:.....|...|...|::..::|.|.|.:......::|:........:.||....|:.
 Worm   115 LKKGDRIGIWGPNTYEWTTTQFASALAGMVLVNINPSYQSEELRYAIEKVGIRALITPPGFKK-- 177

  Fly   156 QELSQGVKSATIILDHSFLP--TAESVSSTSMYAKQLVAIQGVI--------------------- 197
            ....|.:|        ..||  |.:....:.:.::.....|.:|
 Worm   178 SNYYQSIK--------DILPEVTLKEPGKSGITSRNFTCFQHLIMFDEEDKIYPGAWKYTDVMKM 234

  Fly   198 -----------VTENTFPNDFYSKAPAMLIYTPNAVNSPKPVLLTHRNIEAQMRCLIGTWHLG-- 249
                       :...|.|:|..:     :.||......||...|||.|:      |...:.:|
 Worm   235 GTEEDRHHLSKIERETQPDDSLN-----IQYTSGTTGQPKGATLTHHNV------LNNAFFVGLR 288

  Fly   250 ------PTDCMLPILSMNRMHAALAAVLSVGGNVV-LQQKFDGHNAWSALLGINSPSKQRVTLFL 307
                  .|...:|    |.::.....|:.|...:. ||.......::.||..:.:..:::.|...
 Worm   289 AGYSEKKTIICIP----NPLYHCFGCVMGVLAALTHLQTCVFPAPSFDALAALQAIHEEKCTALY 349

  Fly   308 AMPIVYKRLIVEYEKMFAKDSRMVEYIVNHCRQKIRLMATAFALLPDSVFYRWREITGQNIYEYY 372
            ..|.::..:|                  ||               |:...|.            |
 Worm   350 GTPTMFIDMI------------------NH---------------PEYANYN------------Y 369

  Fly   373 GMMETGLVLGHP----LNKRQRDSPH-------NGPTAVA----MANNTAPNDYRPGTLGSPLKG 422
            ..:.:|.:.|.|    |.:|.....|       .|.|..:    |:....|.:.|..::|..:..
 Worm   370 DSIRSGFIAGAPCPITLCRRLVQDMHMTDMQVCYGTTETSPVSFMSTRDDPPEQRIKSVGHIMDH 434

  Fly   423 VTARLISNKGDELITCKNELGGSVDSGLIPVEDIGGDASLAGTIIGELQIAGSNLVSNTLANNNQ 487
            :.|.::..:     .|           ::|           ..:.||:.:.|.:::
 Worm   435 LEAAIVDKR-----NC-----------IVP-----------RGVKGEVIVRGYSVM--------- 463

  Fly   488 EMEHKGTTNNEEQ---ENNQDGFFKTGDICA-YRNGNFYFLSKSSDIFTVGGYKVYGSEIKKVLI 548
                :...|:|||   |..||.::.||||.. :.||....:.:|.|:...||..:|.:|:::.|.
 Worm   464 ----RCYWNSEEQTKKEITQDRWYHTGDIAVMHDNGTISIVGRSKDMIVRGGENIYPTEVEQFLF 524

  Fly   549 SHPNINDVAVLGIPNKMWGHRLGVICI-----VSPDADIDLDAIKTYCYRHLPAHKCP--TVFK 605
            .|.::.||.::|:|::.:|.   |:|.     .|.:.....:.||.:|...:...|.|  .:||
 Worm   525 KHQSVEDVHIVGVPDERFGE---VVCAWVRLHESAEGKTTEEDIKAWCKGKIAHFKIPRYILFK 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	109/624 (17%)
		AFD_class_I	58..607	CDD:302604	111/622 (18%)
acs-1	NP_001023937.1	PRK08315	53..615	CDD:236236	117/649 (18%)
		FACL_like_2	252..604	CDD:213284	83/437 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R434
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.940