DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18155 and acs-21

DIOPT Version :9

Sequence 1:	NP_996360.2	Gene:	CG18155 / 31668	FlyBaseID:	FBgn0029945	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_503845.1	Gene:	acs-21 / 178751	WormBaseID:	WBGene00016849	Length:	517	Species:	Caenorhabditis elegans

Alignment Length:	494	Identity:	103/494 - (20%)
Similarity:	180/494 - (36%)	Gaps:	113/494 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 GGAALSNVTYLCSNNALWIAIQWSCWISGQVAVPLESGQAIDQLQRQASNCKTKLLIATKEFESL 154
            |...::.|:......||:.|    |...|.:.||:.......:......:.|..|.|..|:....
Worm    73 GDRVMARVSKTTDTAALYAA----CLQIGALYVPVNPALTQSEAAHYVKDAKPSLWITCKDDADQ 133

  Fly   155 AQELSQGVKSATIILDHSFLPTAESVSSTSMYAKQLVAIQGVIVTENTFPNDFYSKAPAMLIYTP 219
            .....:.:|  |:.:|:......|.|.:.....::...:...:...|.          |.:.:|.
Worm   134 IAMFQRVLK--TVCIDNPVEVINEKVLADEAGKRKACTMIEHVEKSNA----------ATICFTS 186

  Fly   220 NAVNSPKPVLLTHRNIEAQMRCLIGTWHLGPTD----CMLPILSMNRMHAALAAVLSVGGNVVLQ 280
            ....:||..:|:|..:......|:..|.....|    | |||...:.::.:|...|....:|:.:
Worm   187 GTTGAPKGAVLSHGALTNNTNALVQEWGFTENDVNLHC-LPIFHAHGLYFSLHCSLFSHSSVIWR 250

  Fly   281 QKFDGHNAWSALLGINSPSKQRVTLFLAMPIVYKRLIVEYEKMFAKDSRMVEYIVNHCRQKIRLM 345
            ..||..:.        |...:..|:|:.:|..|.||:.  ...|.|:|          .:||||.
Worm   251 PNFDAEDC--------SKHLKNATVFMGVPTFYSRLLA--TNNFNKES----------FEKIRLF 295

  Fly   346 ATAFALLPDSVFYRWREITGQNIYEYYGMMETGLVLGHPLNKRQRDSPHNGPTAVAMANNTAPND 410
            .:..|.|.......:.:.|||.|.|.|||.|.|::..:||..::
Worm   296 ISGSAPLSVPTLEEFEKRTGQVILERYGMTEAGVIASNPLKGKR--------------------- 339

  Fly   411 YRPGTLGSPLKGVTARLISNKGDELITCKNELGGSVDSGLIPVEDIGGDASLAGTIIGELQIAGS 475
             :.||:|..||||..|:..|                                     ||::|...
Worm   340 -KAGTVGQALKGVQCRVTEN-------------------------------------GEIEIKSD 366

  Fly   476 NLVSNTLANNNQEMEHKGTTNNEEQENNQDGFFKTGDICAY-RNGNFYFLSKSSDIFTVGGYKVY 539
            ::.|          |:.......::|..:||:|||||:.:. ::|......:|.|:...||..:|
Worm   367 SIFS----------EYWKNPEKTKEEFTEDGWFKTGDVGSLDKDGYLTIGGRSKDMIISGGENIY 421

  Fly   540 GSEIKKVLISHPNINDVAVLGIPNKMWGHRLGVICIVSP 578
            ..||:..:.|...:.:.||:..|:..:|.  .|:.:|.|
Worm   422 PKEIEDAIDSIEFVKESAVIAAPHPDFGE--AVVAVVVP 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	103/494 (21%)
CG18155	NP_996360.2	AFD_class_I	58..607	CDD:302604	103/494 (21%)
acs-21	NP_503845.1	MCS	38..505	CDD:213307	103/494 (21%)
acs-21	NP_503845.1	PRK07514	40..517	CDD:181011	103/494 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166459
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55233
OrthoDB	1	1.010	-	-		D229996at33208
OrthoFinder	1	1.000	-	-		FOG0002270
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R434
SonicParanoid	1	1.000	-	-		X2297
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790