DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18155 and acsf3

DIOPT Version :9

Sequence 1:	NP_996360.2	Gene:	CG18155 / 31668	FlyBaseID:	FBgn0029945	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_001121382.2	Gene:	acsf3 / 100158470	XenbaseID:	XB-GENE-964811	Length:	589	Species:	Xenopus tropicalis

Alignment Length:	579	Identity:	163/579 - (28%)
Similarity:	278/579 - (48%)	Gaps:	93/579 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 SNVVVPTFKKAMLYPDEIAVKDINGEYTYFQLYMAAKRLGIQISNICGGAALSN----VTYLCSN 103
            |:.|||.|.:|..:.:..|:.|.:|::||.:||:.::.|...|..:.|..:.:|    |::||.|
Frog    52 SSHVVPVFSRAPFFSERTAMVDQHGKHTYKELYIRSQALSKMIIQLLGHPSRNNPPERVSFLCPN 116

  Fly   104 NALWIAIQWSCWISGQVAVPLESGQAIDQLQRQASNCKTKLLIATKEFESLAQELSQGVKSATII 168
            |:.::..||:.|:||.:||||.......:|:....:.::.|::|.:.:.::...|::.:.
Frog   117 NSSYVVCQWAVWMSGAIAVPLYKSHPPSELKYILQDSQSALVVAEESYANVMNPLAEQLG----- 176

  Fly   169 LDHSFLPTAESVSSTSMYAKQLVAIQGVIVTENTFPNDFYSKAPAMLIYTPNAVNSPKPVLLTHR 233
                 :|......|.|::..:|  :|.:.|::  ...|:..:. ||:|||......||.||.||.
Frog   177 -----IPVLTMSGSQSLHPSEL--LQEIEVSK--LELDWKDRG-AMIIYTSGTTGRPKGVLSTHY 231

  Fly   234 NIEAQMRCLIGTWHLGPTDCMLPILSMNRMHAA---LAAVLSVGGNVVLQQKFDGHNAWSALLGI 295
            |:.:.:..|:..|.....|.:|.:|.::.:|..   |...|.||...|:...|.....|...|..
Frog   232 NLYSMVSALVTEWGWTKEDSILHVLPLHHVHGVVNKLMCPLWVGATCVMLPDFCPQKVWQHFLRR 296

  Fly   296 NSPSKQRVTLFLAMPIVYKRLIVEYEKMFAKDSRMVEYIVNHCRQKIRLMATAFALLPDSVFYRW 360
            ::||   :.:|:|:|.:|.:||..||:.|. .|.:.|::...|:::||||.:..:.||..:..||
Frog   297 DAPS---INIFMAVPTIYSKLISYYEQHFT-HSNVREFVRAACQERIRLMVSGSSALPVPILERW 357

  Fly   361 REITGQNIYEYYGMMETGLVLGHPLNKRQRDSPHNGPTAVAMANNTAPNDYRPGTLGSPLKGVTA 425
            :||||..:.|.|||.|.|:.|.:||         :||..             ||.:|:||.||..
Frog   358 QEITGHTLLERYGMTEIGMALTNPL---------HGPRV-------------PGAVGNPLPGVEV 400

  Fly   426 RLISNKGDELITCKNELGGSVDSGLIPVEDIGGDASLAGTII--------GELQIAGSNLVSNTL 482
            |.::....:             .|........||::  ||::        ||||:.|..:..
Frog   401 RTVTQNPRK-------------EGTSYTVHAHGDST--GTMVSVGLENREGELQVQGPAVFK--- 447

  Fly   483 ANNNQEMEHKGTTNNEEQENNQDGFFKTGDICAYRNGNFYFLSKSS-DIFTVGGYKVYGSEIKKV 546
                   |:....:..::....||:|||||...|::|.::.|.::| ||...|||||...|:::.
Frog   448 -------EYWNKPHETQEAFTSDGWFKTGDTAVYKDGTYWILGRTSVDIIKSGGYKVSALEVERH 505

  Fly   547 LISHPNINDVAVLGIPNKMWGHRLGVICIVSPDADIDLDAIK--------TYCYRHLPA 597
            |:.||:|.||||:|.|:..||.|:..|..:.....:.|..:|        .||   :||
Frog   506 LLGHPSITDVAVIGAPDVTWGQRVAAIVKLRDGHALSLQELKEWARAVMAPYC---IPA 561

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18155	NP_996360.2	CaiC	53..604	CDD:223395	158/569 (28%)
CG18155	NP_996360.2	AFD_class_I	58..607	CDD:302604	157/564 (28%)
acsf3	NP_001121382.2	CaiC	61..582	CDD:223395	158/570 (28%)
acsf3	NP_001121382.2	MCS	67..579	CDD:213307	157/564 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	178	1.000	Domainoid score	I3521
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	232	1.000	Inparanoid score	I3342
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D229996at33208
OrthoFinder	1	1.000	-	-		FOG0002270
OrthoInspector	1	1.000	-	-		oto105336
Panther	1	1.100	-	-	LDO	PTHR24096
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R434
SonicParanoid	1	1.000	-	-		X2297
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.190