Protein Alignment Dok and dok4

DIOPT Version :9

• Sequence 1: NP_572391.1
• Gene: Dok / 31667
• FlyBaseID: FBgn0029944
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_697365.2
• Gene: dok4 / 568912
• ZFINID: ZDB-GENE-041008-91
• Length: 332
• Species: Danio rerio
• Alignment Length: 385
• Identity: 89/385 - (23%)
• Similarity: 139/385 - (36%)
• Gaps: 88/385 - (22%)

  Fly     8 LAGYLNVPTQTGFSLNRISKKKACSRYC-LLF-KASRHGIARLEMCESKEDRN----PKIFTLEN 66
            :|...|...:.|:...| |:|....|.| |:| |:|..|..|||....::...    ||:..:.|
Zfish     1 MASNFNDIVKQGYVRMR-SRKLGIYRRCWLVFKKSSSKGPRRLEKYPDEKSAYIRACPKVTEISN 64

  Fly    67 CVKITQEPPPERLIHIVKRQA---------TLTLSTSSEEELKDWITALQTVAFCDTSPSGGIGA 122
            ...:|      ||....||||         :.|.:..||.|.::|...|...  |..:....|..
Zfish    65 VKNVT------RLPRDTKRQAVAIVFTDDTSRTFTCESELEAEEWFKTLSIE--CLGTRLNDISL 121

  Fly   123 IEED---NDLYCSSFDGLFIITLIPSEASIRCCIEPKTY---MLQMTPTELQL-KSEDLGATIAM 180
            .|.|   ..:.|...: .|.:.|:|       |.....|   |:|:|...:.| ...:....:..
Zfish   122 GEPDLLAAGVQCEHTE-RFNVFLLP-------CPNLDIYGECMMQITHENIYLWDIHNPRTKLVT 178

  Fly   181 WPYRFIRKYGYRDGKFTFEAGRKCTTGEGVFTLDHTNPQEVFRCMSAKMKSMKKLISGDSLSTLE 245
            ||...:|:||....:|||||||.|.:|||::|......:::::.:.:              |||.
Zfish   179 WPLCSLRRYGRDATRFTFEAGRMCDSGEGLYTFQTREGEQIYQRVHS--------------STLA 229

  Fly   246 CGENQFSAAAGMEPGSRSPLPPSPSSNPHGGEFEINSTQSCISLRGFISSNDSLNNFSAGGGGAS 310
            ..|........||..|:     ..|..|.|..:....|       ..:..:...::.:   |..:
Zfish   230 IAEQHKRVLMEMEKNSK-----LLSKGPEGTSYPCTPT-------AILPRSAFWHHIT---GSQA 279

  Fly   311 GATATGGGVLGSTGGITLSVPANSNSNSSSSKHIPNKPPRKS----------PTTHCDKY 360
            |..:..|.:.|.        |.....:...||.:|  |.|.|          |.||...|
Zfish   280 GVDSANGDLYGD--------PQPGMDSDLFSKRLP--PERHSTLPMGRGCSQPPTHYPSY 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dok	NP_572391.1	PH	6..110	CDD:214574	32/116 (28%)
		PH	6..107	CDD:278594	31/113 (27%)
		PH-like	138..232	CDD:302622	26/97 (27%)
dok4	XP_697365.2	PH	8..111	CDD:278594	30/111 (27%)
		PH_DOK4_DOK5_DOK6	9..113	CDD:270197	31/112 (28%)
		PTB_DOK4_DOK5_DOK6	133..235	CDD:241318	31/123 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574599
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4047
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840