Protein Alignment Dok and Dok5

DIOPT Version :9

• Sequence 1: NP_572391.1
• Gene: Dok / 31667
• FlyBaseID: FBgn0029944
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_006235735.1
• Gene: Dok5 / 502694
• RGDID: 1562846
• Length: 308
• Species: Rattus norvegicus
• Alignment Length: 347
• Identity: 79/347 - (22%)
• Similarity: 126/347 - (36%)
• Gaps: 80/347 - (23%)

  Fly     7 VLAGYLNVPTQTGFSLNRISKKKACSRYCLLFKASRHGIARLEMCESKEDRNP------KIFTLE 65
            |..||:.:.::      |:...:.|  :.:..|||..|..|||  :..::|..      |:..|.
  Rat     9 VKQGYVRIRSR------RLGIYQRC--WLVFKKASSKGPKRLE--KFSDERAAYFRCYHKVTELN 63

  Fly    66 NCVKITQEPPPERLIHIV----KRQATLTLSTSSEEELKDWITALQTVAFCDTSPSGGIGAIEED 126
            | ||.....|.....|.:    ....:.|.:..|:.|..:|...||...         :|.  ..
  Rat    64 N-VKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQIEC---------VGT--RI 116

  Fly   127 NDLYCSSFDGL-----------FIITLIPS---EASIRCCIEPKTYMLQMTPTELQL-KSEDLGA 176
            ||:.....|.|           |.:.|:||   :....|.       ||:|...:.| ..::...
  Rat   117 NDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECA-------LQITYEYICLWDIQNPRV 174

  Fly   177 TIAMWPYRFIRKYGYRDGKFTFEAGRKCTTGEGVFTLDHTNPQEVFRCMSAKMKSMKKLISGDSL 241
            .:..||...:|:||.....|||||||.|.||||:|.....:.:.:::    |:.|....|:....
  Rat   175 KLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQ----KVHSAALAIAEQHE 235

  Fly   242 STLECGENQF------SAAAGMEPGSRSPLPPSPSSNPHGGEFEINSTQSCISLRGFISSNDSLN 300
            ..|:..:|..      ...|..|..|.:.|           .::..:|.||.:|  :..|.....
  Rat   236 RLLQSVKNSMVMMLDRQGPALEETASLTVL-----------TWKKETTTSCCTL--YEKSEVQTG 287

  Fly   301 NFSAGGGGASGATATGGGVLGS 322
            :|....||......   |:|||
  Rat   288 SFVCSNGGLMFLEP---GILGS 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dok	NP_572391.1	PH	6..110	CDD:214574	26/112 (23%)
		PH	6..107	CDD:278594	24/109 (22%)
		PH-like	138..232	CDD:302622	28/97 (29%)
Dok5	XP_006235735.1	PH	8..111	CDD:278594	26/112 (23%)
		PH_DOK4_DOK5_DOK6	9..113	CDD:270197	26/123 (21%)
		PTB_DOK4_DOK5_DOK6	133..235	CDD:241318	30/112 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335299
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4047
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21258
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840