Protein Alignment Dok and Frs3

DIOPT Version :9

• Sequence 1: NP_572391.1
• Gene: Dok / 31667
• FlyBaseID: FBgn0029944
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001017382.2
• Gene: Frs3 / 316213
• RGDID: 1310226
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 94/477 - (19%)
• Similarity: 160/477 - (33%)
• Gaps: 152/477 - (31%)

  Fly   138 FIITLIPSEASIRCCIEPKTYMLQMTPTELQLKSEDLGATIAMWPYRFIRKYGYRDGKFTFEAGR 202
            |.:|.:..|.     :|..:.::::|.:||.|......|  ..|||..:|:|||....|:||:||
  Rat    21 FKVTNVDDEG-----VELGSGVMELTQSELVLHLHQQEA--VRWPYLCLRRYGYDSNLFSFESGR 78

  Fly   203 KCTTGEGVFTLDHTNPQEVFRCMSAKMKSMKKLISGDSLSTLECGENQFSAAAGMEPGSRSPLPP 267
            :|.||:|:|....:..:|:|..       ::.|:..:|::..|                 .|:..
  Rat    79 RCQTGQGIFAFKCSRAEEIFNL-------LQDLMQCNSINVTE-----------------EPVII 119

  Fly   268 SPSSNPHGGEFEINSTQSCISLRGFISSNDSLNNFSAGGGGASGATATGGGVLGSTGGITLSVPA 332
            :.:|:|...:....|:|.    .|:     ::::||.|..|..|
  Rat   120 TRNSHPQELDLPRGSSQP----TGY-----TVSSFSNGFPGCPG--------------------- 154

  Fly   333 NSNSNSSSSKHIPNKPPRKSPTTHCDKYRNIVKYEPVAITTISSPSANSDVNSSVILKPLEGESI 397
             .....||:...|:....:.|:...:..:.::..:..:.|.:::|:...|..|...|:|
  Rat   155 -EGPRFSSAPRRPSTSSLRHPSPGEESTQTLIASDEQSHTYVNTPTGEEDRRSRHCLQP------ 212

  Fly   398 SLPETAADLPP-------------------------------------------DLPL---RNES 416
             |||.....||                                           |.||   .||.
  Rat   213 -LPEGRVPFPPQTQVSDQRDPQVFLQPGQVKFVLGPTPARRQVMKCQSLCPSMQDPPLHNNNNEG 276

  Fly   417 ASKAP-PPERDYECIENITE---AWR----TRGVGDVRHS-------ERMPILCDTSEFVRQRSV 466
            .|:.| .|:..||.:....:   .||    .||...:.|.       |.:|.|....|...|:..
  Rat   277 PSECPAQPKCTYENVSGGLQQGAGWRLSPEERGWSGLAHRRAALLHYENLPPLPPVWESQVQQLG 341

  Fly   467 SKSTCGSQNTPKIIDIDIGEGCT-SATSISESNYDRLDFLSPNNKTSSGYKTIVNVTPGNRIRCS 530
            .::  |.       |.|..:|.| |:....:...|......|.:..:|.........|..|.|.|
  Rat   342 GEA--GD-------DGDSKDGLTPSSNGFPDGEEDETPLQKPTSTRASARSHSSFPVPLTRRRGS 397

  Fly   531 ------------PPPPNEYELI 540
                        |.||.:...|
  Rat   398 PRVFNFDFRRPGPEPPRQLNYI 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dok	NP_572391.1	PH	6..110	CDD:214574
		PH	6..107	CDD:278594
		PH-like	138..232	CDD:302622	28/93 (30%)
Frs3	NP_001017382.2	PTB_FRS2	15..106	CDD:269913	29/98 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..205		16/110 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..414		16/84 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	426..493

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335297
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930