Protein Alignment Dok and rog-1

DIOPT Version :9

• Sequence 1: NP_572391.1
• Gene: Dok / 31667
• FlyBaseID: FBgn0029944
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_493958.2
• Gene: rog-1 / 186242
• WormBaseID: WBGene00018819
• Length: 599
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 124/558 - (22%)
• Similarity: 199/558 - (35%)
• Gaps: 185/558 - (33%)

  Fly   160 LQMTPTELQL---KSEDLGATIAMWPYRFIRKYGYRD-GKFTFEAGRKCTTGEGVFTLDHTNPQE 220
            |::|.|.:.|   |.|.|     :||...||:|||.. |.|.||:||:|.:|||:||.......|
 Worm    55 LRVTRTTITLEISKKECL-----VWPLPLIRRYGYTSAGIFFFESGRRCESGEGMFTFQSKKADE 114

  Fly   221 VFRCMSAKMK-----SMKKL---------------ISGDSLSTLECGENQFSAAAGMEPGSRSPL 265
            :|:.:.:.::     ||:|.               ||...:|    ..:..|:..|::..| .||
 Worm   115 IFQLIQSLIEEFANTSMEKQNMENSFRYQRQQSVPISSRRMS----NTSNTSSVFGLKYSS-PPL 174

  Fly   266 PPSPSSNPHGGEFEINSTQSCISLRGFISSNDSL-NNFSAGGGGASGATATGGGVLGSTGGITLS 329
            .|.||:...                   :||.|| :|||...|     :.|...:..|.......
 Worm   175 MPIPSARDR-------------------NSNTSLASNFSIRNG-----SHTVRPMPSSVQRFRSE 215

  Fly   330 VPANSNSNSSSSKHIPNKPPRKSPTTHCDKYRNIVKYEPVAITTISSPSANSDVNSSVILKPLEG 394
            |.|..||...:|            :.:...:.:.:.|.       |...::.|..|..|..|:..
 Worm   216 VFAGMNSEVLTS------------SMNSSGFNDSIGYH-------SYHRSSFDPRSGRINTPMRP 261

  Fly   395 ESISLPETAADLPPDLPLRNESASKAPP-------PERDYECIENITEAWRTRGVGDVRHSERMP 452
            .|::.....||         ||:|...|       |...:..:.|   :....|.|..|.|:.:
 Worm   262 RSVTDTSDYAD---------ESSSYGYPSSHHHHLPHDSFHALNN---SVGMGGGGATRGSKLL- 313

  Fly   453 ILCDTSEFVRQRSVSKSTCGSQN--TPKIIDIDIGE----------GCTSATSISESNYDRLD-F 504
                 ...|.:|:..|:: |..|  .|..|:|...|          ..||::|::.|....:. .
 Worm   314 -----GNIVTERTNPKAS-GISNGILPPYINISPKEVPSSSRHHYYAATSSSSMTASAASEVSAA 372

  Fly   505 LSPNNK---TSSGYKTIVN--VTPGNRI-RCSPPPPNEYEL---IASPDTESFRK---------- 550
            ||..|:   :.||..|..:  .|..::: ||:|||.:..:|   ...|.|...::
 Worm   373 LSAMNRDISSGSGSSTAASATATTSSKLPRCTPPPVSNRQLKRYAMVPGTSMSKRRISREDAKRA 437

  Fly   551 -----------------------ADDSH------------RGYGV--LRKASTTTNNN-----NL 573
                                   ||:::            ||..|  |....|||..:     :.
 Worm   438 FLSSDPRVGHVIDDPRYAAVNVEADENYANLRDIQTDKIMRGIDVETLTNLHTTTEPSPPLPRHH 502

  Fly   574 GISNSNISGGSSTITTATANKGGNLEAAAIDHRSYNGL 611
            .|..|..:|.:|:..:|.|...|.|:.:       |||
 Worm   503 QIQASTTAGATSSSLSAAAGTRGTLKPS-------NGL 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dok	NP_572391.1	PH	6..110	CDD:214574
		PH	6..107	CDD:278594
		PH-like	138..232	CDD:302622	28/80 (35%)
rog-1	NP_493958.2	PTB_FRS2	34..124	CDD:269913	28/73 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5513
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940