Protein Alignment Dok and dok5

DIOPT Version :10

• Sequence 1: NP_572391.1
• Gene: Dok / 31667
• FlyBaseID: FBgn0029944
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_002935431.1
• Gene: dok5 / 100496159
• XenbaseID: XB-GENE-986681
• Length: 306
• Species: Xenopus tropicalis
• Alignment Length: 294
• Identity: 67/294 - (22%)
• Similarity: 112/294 - (38%)
• Gaps: 68/294 - (23%)

  Fly     7 VLAGYLNVPTQTGFSLNRISKKKACSRYCLLFKASRHGIARLEMCESKEDRNP------KIFTLE 65
            |..||:.:.::      |:...:.|  :.:..|||..|..|||  :..::|..      |:..|.
 Frog     9 VKQGYVKIRSR------RLGIYQRC--WLVFKKASSKGPKRLE--KFSDERAAYFRCYHKVTELN 63

  Fly    66 NCVKITQEPPPERLIHIVKRQA---------TLTLSTSSEEELKDWITALQTVAFCDTSPSGGIG 121
            |...|.      ||....|:.|         :.|.:..||.|..:|...|.|...........:|
 Frog    64 NVKNIL------RLPKTTKKHALGIFFTDDTSKTFACESELEADEWCKVLHTECLGTRINDISLG 122

  Fly   122 AIEEDNDLYCSSFD----GLFIITLIPS-------EASIRCCIEPKTYMLQMTPTELQLKSEDLG 175
                :.||..:..:    ..|.:.|:||       |.:::...| ...:..:....::|.|
 Frog   123 ----EPDLLATGVEREQNERFNVYLMPSPNLDIHGECTLQITFE-NICLWDIQNPRMKLVS---- 178

  Fly   176 ATIAMWPYRFIRKYGYRDGKFTFEAGRKCTTGEGVFTLDHTNPQEVF-RCMSAKM---KSMKKLI 236
                 ||...:|:||.....|||||||.|.||||:|.......:.:: :..||.:   :..::|:
 Frog   179 -----WPLSSLRRYGRDPAWFTFEAGRMCDTGEGLFIFQTREGEAIYHKVHSAALAIAEQHERLL 238

  Fly   237 SG--DSLSTLECGENQFSAAAGMEPGSRSPLPPS 268
            ..  :|:..:...|...|.      .:..|||.|
 Frog   239 QSVKNSMLQMRMSERTVSL------NTMVPLPRS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dok	NP_572391.1	PH	6..107	CDD:459697	26/114 (23%)
		IRS	138..233	CDD:460473	28/105 (27%)
dok5	XP_002935431.1	PH_DOK4_DOK5_DOK6	9..113	CDD:270197	28/119 (24%)
		PTB_DOK4_DOK5_DOK6	133..235	CDD:241318	28/111 (25%)