Protein Alignment Dok and dok2

DIOPT Version :10

• Sequence 1: NP_572391.1
• Gene: Dok / 31667
• FlyBaseID: FBgn0029944
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_002932742.2
• Gene: dok2 / 100487659
• XenbaseID: XB-GENE-982227
• Length: 416
• Species: Xenopus tropicalis
• Alignment Length: 474
• Identity: 115/474 - (24%)
• Similarity: 194/474 - (40%)
• Gaps: 116/474 - (24%)

  Fly     7 VLAGYLNVPTQTGFSLNRISKKKACSRYCLLFKASRHGIARLEMCESKE----DRNP---KIFTL 64
            |..|.|::..|..|.      ||....:.:|::|:..|:|||||.|..:    .|.|   |:..|
 Frog     6 VKQGALHLQHQQRFG------KKWKKVWGVLYEATCSGLARLEMFEGSQPPDSGRKPECWKLLQL 64

  Fly    65 ENCVKITQ-----EPPPERLIHIVKRQATLTLSTSSEEELKDWITALQTVAF----------CDT 114
            ..||.:::     .|...|...|...|....|::.:.|: ..|:.||.::||          ...
 Frog    65 SECVSVSERNGEGSPKDTRSFCIETAQRVYLLASETSEQ-PGWVKALCSLAFPQERLPLERKTSQ 128

  Fly   115 SPSGGIGAIEEDNDLYCSSFDGLFIITLIPSEASIRCCIEPKTYMLQMTPTELQLKSEDLGATIA 179
            .|..|:..  ::|:||.::.:..|::.:.|:|||:||.:. ..|.|....:.|.|:....|:::.
 Frog   129 PPESGLHL--QENELYSTTRETGFVVRIRPTEASVRCGLN-GIYTLSTENSCLSLRDRQTGSSLY 190

  Fly   180 MWPYRFIRKYGYRDGKFTFEAGRKCTTGEGVFTLDHTNPQEVFRCMSAKMKSMKKLISGDSLSTL 244
            .|||.::|::|.....|:|||||:||:|||.|..:.....::|:.:...:.:.|:.:|.::
 Frog   191 NWPYPYLRRFGRDKSMFSFEAGRRCTSGEGSFEFETPLGGQIFQAIECAINNKKEQVSEEA---- 251

  Fly   245 ECGENQFSAAAGMEPGSR----SPLPPSPS-SNPHGGEFEINSTQSCISLRGFISSN-------D 297
                         .||||    |.:|..|: |.|        ..||.:..:..|...       |
 Frog   252 -------------PPGSRKRTTSLVPKGPAVSGP--------CPQSSVVGKPSIQEESEYAVPFD 295

  Fly   298 SLNNFSAGGGGASGATATG-GGVLGSTGGITLSVPANSNSNSSSSKHIP--NKPPRKSPTTHCDK 359
            .:         |....||| ||:||                    .|||  :|.|:..|....:.
 Frog   296 KV---------AQNLLATGFGGLLG--------------------PHIPQQDKRPKARPAGQAEP 331

  Fly   360 Y-------RNIVKYEPVAITTISSPSANSDVNSSVILKP-LEG-ESISLPETAADLPPDLPLRNE 415
            .       .|.|..||..|.:.:..:..:|.:.:....| |.| :..::|..:.   .|...:.|
 Frog   332 IYDEPGTPHNPVYDEPEVIRSEAWKTQATDAHETGYEFPYLPGWDDYAVPRGSG---ADGEQQRE 393

  Fly   416 SASKAPPPERDYECIENIT 434
            :.......||:|   :|||
 Frog   394 AEEWGTGGEREY---DNIT 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dok	NP_572391.1	PH	6..107	CDD:459697	30/111 (27%)
		IRS	138..233	CDD:460473	30/94 (32%)
dok2	XP_002932742.2	PH-like	7..115	CDD:473070	30/114 (26%)
		PH-like	150..244	CDD:473070	30/94 (32%)