Protein Alignment Dok and frs3

DIOPT Version :9

• Sequence 1: NP_572391.1
• Gene: Dok / 31667
• FlyBaseID: FBgn0029944
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: XP_002662545.2
• Gene: frs3 / 100330147
• ZFINID: ZDB-GENE-131121-119
• Length: 627
• Species: Danio rerio
• Alignment Length: 638
• Identity: 135/638 - (21%)
• Similarity: 211/638 - (33%)
• Gaps: 196/638 - (30%)

  Fly   125 EDNDLYCSSFDGLFIITLIPSEASIRCCIEPKTYMLQMTPTELQLKSEDLGATIAMWPYRFIRKY 189
            :||.|      ..|.:|.:..|.:     |..:..:::|.|||.|.:....|  ..|||..:|:|
Zfish    14 QDNHL------NKFKVTNVDDEGN-----ELGSGTMELTQTELILHTRKRDA--IRWPYLCLRRY 65

  Fly   190 GYRDGKFTFEAGRKCTTGEGVFTLDHTNPQEVFRCMSAKMKSMKKLISGDSLSTLECGENQFSAA 254
            ||....|:||:||:|.||:|:|....:..:|:|..       :::|:..:|::.:|  |......
Zfish    66 GYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNL-------LQELMQCNSINVVE--EPMIMTR 121

  Fly   255 AGMEPGSRSPLPPSPSSNP-----------HGGEFEINSTQSCI------SLRGF---------- 292
            .|..|....|..|...:.|           .|.....:|:|..:      ||.|.
Zfish   122 PGHAPEMDMPRTPQTPNTPAFPMQGFPNGYPGYPISADSSQPSLTNDHRHSLMGLDDQTHTYVNT 186

  Fly   293 ------ISSNDSLNNF----SAGGGGASGATAT--GGGVLGSTG--------------------- 324
                  :||...:::.    .|....|:..|.|  ||.:.|..|
Zfish   187 VGMETDLSSRHCVHSLPEVRPATYPEATTTTTTIRGGPIPGQPGMHCCPLDDPHKDPQVFLQPGA 251

  Fly   325 -------GITLSVPANSN-SNSSSSKHIPNK---------------PPRKSPTTH---------- 356
                   |.|   ||..: ......:|:|:.               ||.....||
Zfish   252 QEVKFMLGPT---PAQRHLMERDRERHVPHSLRAPDGSSETEGEETPPVHMCNTHSYHHCHHLMH 313

  Fly   357 -------CDK----YRNI-----VKYEPVAITTIS-SPSANSDVNSSVILKPLEGESISLPETAA 404
                   |.:    |.||     .:.:.::.:|:| |.|..|..:||.     .|:|.:...
Zfish   314 RHPSMEPCPESQLTYENINGLRGARRQRLSPSTVSQSQSLGSSSSSST-----TGDSRTHTH--- 370

  Fly   405 DLPPDLPLRNESASKAPPPERDYECIENITEAWRTRGVGDVRHSERMPILCDTSEF-VRQRSVSK 468
              |..|||.:...|..||  :.|.|...:..|...|..  :.:.|.:|.|....|: ..||...:
Zfish   371 --PHSLPLTHTHTSSLPP--QGYGCDRGMVAAGHRRTA--LLNYENLPSLPPVWEYRALQREEEE 429

  Fly   469 STCGSQNTPKIIDIDIGEGCTSATSISESNYDRLDFLSPNNKTSSGY--------------KTIV 519
                        |.|..|.........|..||..:: |....|.:||              :..|
Zfish   430 ------------DQDEDEDEDEYEEEEEEEYDEYEY-SEGPATPNGYHQESGGGGIHRDALQNYV 481

  Fly   520 N---VTPGNRIR-CSPPPPNEYELIASPDTESFRKADDSHRGYGVLRK--------ASTTTNNNN 572
            |   :.|..|:| ..||.|:..|.........||: ..:.||..:..:        .|...|...
Zfish   482 NTEQLPPPTRLRHACPPHPHPPERANRVFNFDFRR-QRAGRGSSICEQHSRHPPPPPSRQLNYIQ 545

  Fly   573 LGISN-----SNISGGSSTITTATANKGGNLEAAAIDHRSYNGLNYTMVSKPK 620
            :.:..     |..|||:.........|.| :.|||....|..|..|.::...|
Zfish   546 VDLEGEPSGCSGHSGGAPVPQRPPPLKRG-MAAAAAPPSSRRGECYAVIDLKK 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dok	NP_572391.1	PH	6..110	CDD:214574
		PH	6..107	CDD:278594
		PH-like	138..232	CDD:302622	29/93 (31%)
frs3	XP_002662545.2	PTB_FRS2	15..106	CDD:269913	33/110 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574597
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5513
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.870