Protein Alignment Atg5 and ATG5

DIOPT Version :9

• Sequence 1: NP_572390.1
• Gene: Atg5 / 31666
• FlyBaseID: FBgn0029943
• Length: 269
• Species: Drosophila melanogaster
• Sequence 2: NP_015176.1
• Gene: ATG5 / 855954
• SGDID: S000006070
• Length: 294
• Species: Saccharomyces cerevisiae
• Alignment Length: 295
• Identity: 62/295 - (21%)
• Similarity: 125/295 - (42%)
• Gaps: 52/295 - (17%)

  Fly     6 EVLRMIWEGQIGICFQADRD--------EIVGIK---PEPFYLMISRLSYLPLVTDKVRKYFSRY 59
            ::.:::|.|::.:....|..        ||..::   |...||    ::|:||:.:|::.:.| :
Yeast     3 DIKQLLWNGELNVLVSIDPSFLMKGSPREIAVLRIRVPRETYL----VNYMPLIWNKIKSFLS-F 62

  Fly    60 ISAEHQDGAVWFDFNGTPLRLHYPIGVLYDLLHPE--------EDSTPWCLT---IHF---SKFP 110
            ......:...||:.|.||:..:||:|||:|.|..:        |:.....||   ||.   ...|
Yeast    63 DPLTDSEKYFWFEHNKTPIPWNYPVGVLFDCLAGKSATFTTSFENQVKDVLTFLRIHLVMGDSLP 127

  Fly   111 EDMLVKLNSKELLESHYMSCLKE-ADVLKHRGLVISAMQKKDHNQLWLGLVNEKFDQFWAVNRRL 174
            ..::...:||...|..:....|: ..:|......|.::...:..:.|..::...|..|..::.::
Yeast   128 PTIIPIASSKTQAEKFWFHQWKQVCFILNGSSKAIMSLSVNEARKFWGSVITRNFQDFIEISNKI 192

  Fly   175 --MEPYGDLESFKNIPLRIYTDDDFTYTQKLISP-ISVGGQKKSLADLMAELSTPVRRAVG---- 232
              ..|       ::|||.|.|... :.|.::..| ||:.|...:|.|:..:: ..|:..:.
Yeast   193 SSSRP-------RHIPLIIQTSRT-SGTFRISQPTISMTGVNPTLKDIEGDI-LDVKEGINGNDV 248

  Fly   233 ---CRTHGIDLHEETQLQWMSEHLSYPDNFLHLSV 264
               |:  ||::.....|..:...|...|.||::::
Yeast   249 MVICQ--GIEIPWHMLLYDLYSKLRSFDGFLYITL 281

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg5	NP_572390.1	APG5	81..264	CDD:282025	44/207 (21%)
ATG5	NP_015176.1	APG5	83..282	CDD:397981	44/210 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344885
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2976
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I1823
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59300
OrthoFinder	1	1.000	-	-		FOG0004713
OrthoInspector	1	1.000	-	-		oto99014
orthoMCL	1	0.900	-	-		OOG6_103775
Panther	1	1.100	-	-	LDO	PTHR13040
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R110
SonicParanoid	1	1.000	-	-		X3313
TreeFam	1	0.960	-	-
	12	11.790