Protein Alignment unc-119 and Unc119b

DIOPT Version :10

• Sequence 1: NP_572389.1
• Gene: unc-119 / 31664
• FlyBaseID: FBgn0025549
• Length: 265
• Species: Drosophila melanogaster
• Sequence 2: NP_780561.1
• Gene: Unc119b / 106840
• MGIID: 2147162
• Length: 251
• Species: Mus musculus
• Alignment Length: 262
• Identity: 136/262 - (51%)
• Similarity: 169/262 - (64%)
• Gaps: 22/262 - (8%)

  Fly    11 VQSSGAGAVTTSSSAAAGSSSSNSGVEANGGSG----------GSSGAAAAGAGASGDAKRPAES 65
            :..|...|.|..|.|..|...:....:...|.|          |.......|:||:...:.....
Mouse     1 MSGSNPKAATAGSQAGPGGLVAGKEEKKKAGGGVLNRLKARRQGPPHTPDDGSGAAVTEQELLAL 65

  Fly    66 SSVTPDEVLHLTKITDDYLCSANANVFEIDFTRFKIRDLESGAVLFEIAKPPSEQYPEGLSSDET 130
            .::.|:.||.|.::|::|||....||:.||||||||||||:|.||||||||        ..||:.
Mouse    66 DTIRPEHVLRLNRVTENYLCKPEDNVYSIDFTRFKIRDLETGTVLFEIAKP--------CISDQD 122

  Fly   131 MLAAAEKLSLDDTADPNAGRYVRYQFTPAFLNLKTVGATVEFTVGSQPLNNFRMIERHFFRDRLL 195
            .  .||:.|:|  .|.:.||:||||||||||.|:|||||||||||.:|:..|||||||:||:|||
Mouse   123 Q--DAEEESVD--VDISVGRFVRYQFTPAFLRLRTVGATVEFTVGDRPVTGFRMIERHYFRERLL 183

  Fly   196 KTFDFEFGFCFPFSKNTVEHIYEFPNLPPDLVAEMISSPFETRSDSFYFVGNRLVMHNKADYAYD 260
            |||||:||||.|.|:||.|||||||.|..|::..||.:|:||||||||||.|:|||||||||||:
Mouse   184 KTFDFDFGFCIPSSRNTCEHIYEFPQLSEDVIRLMIENPYETRSDSFYFVDNKLVMHNKADYAYN 248

  Fly   261 GG 262
            ||
Mouse   249 GG 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-119	NP_572389.1	GMP_PDE_delta	89..259	CDD:428436	112/169 (66%)
Unc119b	NP_780561.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		11/54 (20%)
		GMP_PDE_delta	89..247	CDD:428436	112/169 (66%)