DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2059 and ephx2

DIOPT Version :9

Sequence 1:	NP_001188553.1	Gene:	CG2059 / 31663	FlyBaseID:	FBgn0029942	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001008642.1	Gene:	ephx2 / 494099	ZFINID:	ZDB-GENE-041212-70	Length:	557	Species:	Danio rerio

Alignment Length:	331	Identity:	69/331 - (20%)
Similarity:	124/331 - (37%)	Gaps:	54/331 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EYSSEIP----DPVELSFDSYTGENPET---------SPPLLTYHGLFGSKQNWRGISKALVRKV 79
            |.:|::.    ||.::| ..|....|..         .||:|..||...|..:||....||. ..
Zfish   218 EVTSDLQPPSCDPEKVS-HGYVNIKPGVKIHYVEMGDGPPVLLCHGFPESWFSWRYQIPALA-DA 280

  Fly    80 SRKVYAIDVRNHGES---PHSSVHNSKAMSEDLRLFMEQRSHPNAACMGHSMGGRSMMYFARKYP 141
            ..:|.|.|::.:|.|   |....::.:.:..||..|:::.:......:||..||..:...|:.:|
Zfish   281 GFRVLAPDMKGYGGSTAPPDIEEYSQEQIMLDLVTFLDKMAIAQVTLVGHDWGGVLVWNMAQFHP 345

  Fly   142 ELVERLIVVDISPISVPRSTGEMTE-----IFDAMVSLDLSPSMSMSEGRKIARE--KLLKATED 199
            |.|..:..::.....|..:|..|.:     |||..:... .|.::.:|..|..:.  ||:..:..
Zfish   346 ERVRAVASLNTPLFPVDPNTNPMEKLMAIPIFDYQIYFQ-KPGVAEAELEKNLKRTFKLMFISSS 409

  Fly   200 ETVDFIMLN----------LRKNPDTGAFSWACNAHVLREFLTRFDK------------YQSNLE 242
            :|..|..|:          ...:||....|...:...|:.:..::.|            |:.|..
Zfish   410 DTGGFPKLSPAGVCQRGGLFVGSPDDPPRSSMLSVSALQFYTEQYSKSGFRGPLNWYRNYERNWR 474

  Fly   243 EL-----PPYTGPTTFICGTRSPYMRREQWPQIQKMFPN-SEIHWLDAGHLVHFEKPQEFLTIVS 301
            .:     .....|...:...:.|.:.......::.:.|| |..|..:.||....|:|.|...|:.
Zfish   475 WMVSRPRAKILMPALMVTAGKDPVLLPAFATGMENLIPNLSRGHIEECGHWTQMERPAELNKILI 539

  Fly   302 EFLNRT 307
            .:|..|
Zfish   540 SWLKET 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2059	NP_001188553.1	PRK10673	38..305	CDD:182637	63/313 (20%)
		Abhydrolase_5	54..>151	CDD:289465	26/99 (26%)
		Abhydrolase	<253..287	CDD:304388	6/34 (18%)
ephx2	NP_001008642.1	HAD-1A3-hyp	3..217	CDD:274054
		HAD_like	<155..203	CDD:304363
		Abhydrolase	237..>358	CDD:304388	29/121 (24%)
		Abhydrolase_1	255..531	CDD:278959	57/277 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910