Protein Alignment CG2059 and MEST

DIOPT Version :9

• Sequence 1: NP_001188553.1
• Gene: CG2059 / 31663
• FlyBaseID: FBgn0029942
• Length: 308
• Species: Drosophila melanogaster
• Sequence 2: NP_002393.2
• Gene: MEST / 4232
• HGNCID: 7028
• Length: 335
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 63/298 - (21%)
• Similarity: 104/298 - (34%)
• Gaps: 76/298 - (25%)

  Fly    52 SPPLLT-YHGLFGSKQNWRGISKALVRKVSRKVYAIDVRNHGES----PHSSVHNSKAMSEDLRL 111
            ||.::. .||...|..:|..|.:.|..:..| |.|:|....|.|    ||   |.|
Human    68 SPEIVVLLHGFPTSSYDWYKIWEGLTLRFHR-VIALDFLGFGFSDKPRPH---HYS--------- 119

  Fly   112 FMEQRSHPNAACMGHSMGGRSMMYFARKYPELVERLIVVDISPISVPRSTGEMTEIFDAMVSLDL 176
            ..||.|...|......:..|.:...:..|.::|.:.::....    ...:|.:|
Human   120 IFEQASIVEALLRHLGLQNRRINLLSHDYGDIVAQELLYRYK----QNRSGRLT----------- 169

  Fly   177 SPSMSMSEG-------RKIAREKLLK------ATEDETVDFIMLNLRKNPDTGAFS-------WA 221
            ..|:.:|.|       |.:..:||||      ......::|.:.:....|..|.::       |.
Human   170 IKSLCLSNGGIFPETHRPLLLQKLLKDGGVLSPILTRLMNFFVFSRGLTPVFGPYTRPSESELWD 234

  Fly   222 CNAHV-----------LREFLTRFDKYQSN-LEELPPYTGPTTFICGTRSPYMRREQWPQI---- 270
            ..|.:           |.:::.:..|::.. :..|...|.|..||.|...|.   ..:|:.
Human   235 MWAGIRNNDGNLVIDSLLQYINQRKKFRRRWVGALASVTIPIHFIYGPLDPV---NPYPEFLELY 296

  Fly   271 QKMFPNSEIHWLDAGHLVHF---EKPQEFLTIVSEFLN 305
            :|..|.|.:..|| .|:.|:   |.|..||.....|:|
Human   297 RKTLPRSTVSILD-DHISHYPQLEDPMGFLNAYMGFIN 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2059	NP_001188553.1	PRK10673	38..305	CDD:182637	62/296 (21%)
		Abhydrolase_5	54..>151	CDD:289465	23/101 (23%)
		Abhydrolase	<253..287	CDD:304388	10/37 (27%)
MEST	NP_002393.2	MhpC	47..321	CDD:223669	58/284 (20%)
		RVIALD	98..103		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1268438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010