DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2059 and Ephx2

DIOPT Version :9

Sequence 1:NP_001188553.1 Gene:CG2059 / 31663 FlyBaseID:FBgn0029942 Length:308 Species:Drosophila melanogaster
Sequence 2:NP_031966.2 Gene:Ephx2 / 13850 MGIID:99500 Length:554 Species:Mus musculus


Alignment Length:322 Identity:68/322 - (21%)
Similarity:113/322 - (35%) Gaps:96/322 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 TSPPLLTYHGLFGSKQNWRGISKALVRKVSRKVYAIDVRNHGES---PHSSVHNSKAMSEDLRLF 112
            :.|.|...||...|..:||....||. :...:|.|||::.:|:|   |....:..:.:.:::..|
Mouse   255 SGPALCLCHGFPESWFSWRYQIPALA-QAGFRVLAIDMKGYGDSSSPPEIEEYAMELLCKEMVTF 318

  Fly   113 MEQRSHPNAACMGHSMGGRSMMYFARKYPELVERLIVV---------DISPISVPRS-------- 160
            :::...|.|..:||...|..:...|..|||.|..:..:         |:||:.|.||        
Mouse   319 LDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPFMPPDPDVSPMKVIRSIPVFNYQL 383

  Fly   161 -----------------------------TG-----EMTEIFDAMVSLDLSPSMSMSEGRKIARE 191
                                         ||     :.|||...:|:....|::|          
Mouse   384 YFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHKATEIGGILVNTPEDPNLS---------- 438

  Fly   192 KLLKATEDETVDFIMLNLRKNPDTGAFSWACNAH---------VLREFLTRFDKYQSNLEELPPY 247
               |.|.:|.::|.:...:|....|..:|..|..         :.|:.|.               
Mouse   439 ---KITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLGRKILV--------------- 485

  Fly   248 TGPTTFICGTRSPYMRREQWPQIQKMFP-NSEIHWLDAGHLVHFEKPQEFLTIVSEFLNRTE 308
              |...:...:...:|.|....::|..| ....|..|.||....|||.|...|:.::| :||
Mouse   486 --PALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKWL-QTE 544

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2059NP_001188553.1 PRK10673 38..305 CDD:182637 65/317 (21%)
Abhydrolase_5 54..>151 CDD:289465 26/108 (24%)
Abhydrolase <253..287 CDD:304388 7/34 (21%)
Ephx2NP_031966.2 Phosphatase 1..224
HAD_sEH-N_like 3..214 CDD:319790
Phosphate binding. /evidence=ECO:0000250|UniProtKB:P34913 123..124
Epoxide hydrolase 233..554 68/322 (21%)
Abhydrolase_1 257..530 CDD:395444 61/303 (20%)
Microbody targeting signal. /evidence=ECO:0000255 552..554
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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