Protein Alignment CG1677 and Zc3h18

DIOPT Version :10

• Sequence 1: NP_572387.1
• Gene: CG1677 / 31662
• FlyBaseID: FBgn0029941
• Length: 1000
• Species: Drosophila melanogaster
• Sequence 2: XP_006531532.1
• Gene: Zc3h18 / 76014
• MGIID: 1923264
• Length: 1008
• Species: Mus musculus
• Alignment Length: 1117
• Identity: 269/1117 - (24%)
• Similarity: 401/1117 - (35%)
• Gaps: 425/1117 - (38%)

  Fly   149 PGSPNAKSQPSSFLSSVRSRSVSPQLYNQAAVDLNISHDDLSDVSDIEGEEKRTSSKNSMRPADE 213
            |.||..:.||:.....:...|.|.|       ||:.:.:   ..||:|.||..|..::......:
Mouse    47 PHSPEDEEQPALSDDDILRESGSEQ-------DLDGAGE---RASDLEEEENATRVQSQEETRSD 101

  Fly   214 NEDGAISNDSLPTLGEED-EVEQKQSTPNGK-ASSGDEKEPFAKETHTDDASNGLAPATALQEDL 276
            .||.|    |.|...::| |..:....|.|. ...||:.|........|:||:           :
Mouse   102 EEDRA----SEPKSQDQDSEAHELSRGPAGSPCEEGDDVEEDGTSDLRDEASS-----------V 151

  Fly   277 VKTHDDDALDFEAEEGECPEQAKEPSPMESTANETNQTKSTTKVSQDEGDD-DGEVDKDGDDKDG 340
            .:..|:..||::.   |.||   ||:|   .|.|....|:..:..:::|:. .||..|......|
Mouse   152 TRELDEHELDYDE---EVPE---EPAP---AAQEEEAEKAGAEEEEEKGEGAPGEEGKPDVQSVG 207

  Fly   341 DDKDTRKDGAGNGCLEDGAGNDSRKDDAGNGCLEEGEEEKDIVSVSTSSSQEKVEEGELEEGEVS 405
            :.:.|.            |..:.:|:| .:|.:::||                :::.:||||||.
Mouse   208 EQEPTE------------AAKEKKKED-DDGEIDDGE----------------IDDDDLEEGEVK 243

  Fly   406 DEDEKRPEETEPKPVCRFY------------------------TRGQCTWGMSCRFLHPGVTDKG 446
            |..:::   ..|:|.|||:                        .:|.|||||||||:||||.|||
Mouse   244 DPSDRK---VRPRPTCRFFMKDVVTPLSTLLPPIPNSIPLRGQVKGNCTWGMSCRFIHPGVNDKG 305

  Fly   447 NYTMFDNVIRPVPMQGGSTGASAPAAPSSTAAPRAGGSAYSSHASATADYHDYRTERPLHHRPPL 511
            ||::.... .|.|..|     :.|..|.                                   ||
Mouse   306 NYSLITKA-EPFPPNG-----APPLGPH-----------------------------------PL 329

  Fly   512 LHAPSIYGAPVHDARTLLPDGAP-VVVENAWERGLRTAKEMMRKANKRKEQDMDFEDKKMNLTLS 575
            :.| :.:|.||.|  .:||...| ...|:|||||||.|||:::||..||||:.|||:|:..:|:.
Mouse   330 MPA-NPWGGPVVD--EILPPPPPEPPTESAWERGLRHAKEVLKKATIRKEQEPDFEEKRFTVTIG 391

  Fly   576 PD--EMEKDSYYLKDRGGSSARSPPPPSANVREQPLNPLSMPLSMHPHAVAHANPRALLPLQYSV 638
            .|  |.:|::...:|   .::|.|    .:||:..|.|             :|:|         .
Mouse   392 EDDREFDKENEVFRD---WNSRVP----RDVRDTTLEP-------------YADP---------Y 427

  Fly   639 YGPPPDRY---GRPQYMPPQYDDVDAY----------GRMTRYRELPPHRMPHYEDDRRSR---- 686
            |....:|:   |:.:....||.:.:.|          .|..|.||....|....|.:||.|
Mouse   428 YDYEIERFWRGGQYENFRVQYTEAEPYHNYRERERERERENRQRERERERERDRERERRQRERER 492

  Fly   687 ------------------------------------------------------PTREVIVQRVE 697
                                                                  |:|:....:.|
Mouse   493 ERERERDKERQRRKEEWERERAKRDEKDRQHRDRDRDKDREKDKEKPKPRSPQPPSRQAEPPKKE 557

  Fly   698 AAG------RGDEWSDPWMRSKSVGR--GSYEREDRRRRDRRSYSSNSSYSTSNSSQSDSSSDS- 753
            :..      |.|||.|||.||||..:  |......|.||.|:  :|.||.|.||||:|.|.|.|
Mouse   558 STSVGPQVKRADEWKDPWRRSKSPKKKLGVSVSPSRARRRRK--TSASSASASNSSRSSSRSSSY 620

  Fly   754 ---------SRSSSPSDHKRRYGSH-KLATATATSRRHGGRAARSPSQIPRRPRRTSKGSLSP-- 806
                     |||||.|.:..|...| ..:.:.:.||......:.||:..|.||...:||..:|
Mouse   621 SGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPPVRTKGEPAPPP 685

  Fly   807 ------SYKRPAVDKRGVGHSPSSKRKKLSSPAPKKFDKLRR-RRSSSSSDSDSSDTSYSDSESG 864
                  |.|:||....    .|.:.:.....|.|.|...||. ||....:.:.....:.|.|.||
Mouse   686 GKAGEKSIKKPAPPPA----PPQATKTTAPGPEPAKPGDLREARRKERQTRTPPRRRTLSGSGSG 746

  Fly   865 SSSSDSSSGSRETPQKRVRATDKALNERKLISKPAEQSTKKRSPISIEIKKTSNMVG--VSALAS 927
            |.||.|.|.||          .::|:    :|..:..|:...|..|:....:.:|..  .|.::|
Mouse   747 SGSSYSGSSSR----------SRSLS----VSSVSSVSSATSSSSSVHSVDSDDMYADLASPVSS 797

  Fly   928 ASNSADSDAEKDHDNGKDKEKDHVKEK-------------------------------------- 954
            ||:.:.:.|:...:.||.|::|.|:|:
Mouse   798 ASSRSPTPAQTKKERGKSKKEDGVREEKRRRDPSAQPPKSSKAPAGGKASQQAAAPQPAVPGQPQ 862

  Fly   955 -------------------DKDCKEK----DKDKD-------------GMKD------------- 970
                               ||..:::    |||:.             |.:|
Mouse   863 QGSFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPAKKANLSPDRGSRDRKSGGRMGSPKPE 927

  Fly   971 ---------------------------------------------KEGKK---SRREELLKQLRA 987
                                                         |.||.   ||||||||||:|
Mouse   928 RQRGQNAKAPAAPADRKRPLSPQSKGSSKVTSVPGKATDTATAGTKSGKASTLSRREELLKQLKA 992

  Fly   988 VEDAIAKKRSKL 999
            ||||||:||:|:
Mouse   993 VEDAIARKRAKI 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1677	NP_572387.1	zf-CCCH_4	419..440	CDD:465626	14/44 (32%)
Zc3h18	XP_006531532.1	zf-CCCH_4	254..299	CDD:465626	14/44 (32%)